Is a regenerative approach viable for the treatment of COPD?

Br J Pharmacol. 2011 May;163(1):106-15. doi: 10.1111/j.1476-5381.2011.01246.x. Treatment of COPD Is a regenerative approach viable for the treatment of COPD? Hind M, Maden M. Source Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London, UK. m.hind@imperial.ac.uk Abstract Degenerative lung diseases such as chronic obstructive pulmonary disease (COPD) are common with huge worldwide morbidity.…

Stem cells and chronic lung disease

Annu Rev Med. 2007;58:285-98. Stem cells and chronic lung disease. Gomperts BN, Strieter RM. Source Mattel Children’s Hospital, Department of Pediatrics, Division of Pediatric Hematology, Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA. bgomperts@mednet.ucla.edu Abstract Stem cells have been shown to contribute to the repair and regeneration of injured lungs.…

Deriving respiratory cell types from stem cells.

urr Stem Cell Res Ther. 2007 Sep;2(3):197-208. Deriving respiratory cell types from stem cells. Olsson F, Denham M, Cole TJ, Hooper SB, Mollard R. Source Department of Physiology, Monash University, Clayton, 3800, Australia. Abstract The reported pluripotential capabilities of many human stem cell types has made them an attractive area of research, given the belief…

Cell based therapy for COPD

[Article in Japanese] Kubo H. Source Department of Geriatrics and Gerontology, Tohoku University Hospital. Abstract To develop a new cell based therapy for chronic obstructive pulmonary disease (COPD), we need to understand 1) the role of tissue-specific and bone marrow-derived stem cells, 2) extracellular matrix, and 3) growth factors. Recently, bronchioalveolar stem cells were identified…

Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease.

Expert Opin Biol Ther. 2010 May;10(5):681-7. Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease. D’Agostino B, Sullo N, Siniscalco D, De Angelis A, Rossi F. Source Department of Experimental Medicine, Second University of Naples, Section of Pharmacology L Donatelli, via S Maria di Costantinopoli, 16-80138 Napoli, Italy. bruno.dagostino@unina2.it Abstract Recent studies…