Stem cells in human neurodegenerative disorders–time for clinical translation?

J Clin Invest. 2010 Jan 4;120(1):29-40 Stem cells in human neurodegenerative disorders–time for clinical translation? Lindvall O, Kokaia Z Stem cell-based approaches have received much hype as potential treatments for neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in animal models of neurodegenerative diseases can improve function by replacing the lost neurons and…

The potential of mesenchymal stem cells for neural repair.

Discov Med. 2010 Mar;9(46):236-42. The potential of mesenchymal stem cells for neural repair. Miller RH, Bai L, Lennon DP, Caplan AI. Source Centers for Stem Cells and Regenerative Medicine, Translational Neuroscience, Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA. rhm3@case.edu Abstract Developing effective therapies for serious neurological insults remains…

Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis.

Brain Res. 2010 Jun 2;1334:65-72. Epub 2010 Mar 28. Human mesenchymal stem cell transplantation protects against cerebral ischemic injury and upregulates interleukin-10 expression in Macacafascicularis. Li J, Zhu H, Liu Y, Li Q, Lu S, Feng M, Xu Y, Huang L, Ma C, An Y, Zhao RC, Wang R, Qin C. Source Institute of Laboratory…

Stem cell transplantation methods.

Adv Exp Med Biol. 2010;671:41-57. Stem cell transplantation methods. Tran KD, Ho A, Jandial R. Source UCSD School of Medicine, San Diego, California, USA. Abstract Just a few short years ago, we still used to think that we were born with a finite number of irreplaceable neurons. However, in recent years, there has been increasingly…

Stem cells in the treatment of stroke.

Adv Exp Med Biol. 2010;671:105-16. Stem cells in the treatment of stroke. Urbaniak Hunter K, Yarbrough C, Ciacci J. Source University of Michigan, Department of Radiation Oncology, UH B2C490, 1500 E. Medical Center Dr., Ann Arbor, Michigan, USA. kurbania@med.umich.edu Abstract Stroke is an often devastating insult resulting in neurological deficit lasting greater than 24 hours.…

A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke.

Stem Cells. 2010 Jun;28(6):1099-106. A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. Lee JS, Hong JM, Moon GJ, Lee PH, Ahn YH, Bang OY; STARTING collaborators. Collaborators (14) Lee JS, Hong JM, Choi JY, Park J, Lee G, Ahn YH, Lee PH, Kang YM, Kim HS, Li,…

Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue.

Exp Transl Stroke Med. 2010 May 28;2(1):11. Induction of neuro-protective/regenerative genes in stem cells infiltrating post-ischemic brain tissue. Yilmaz G, Alexander JS, Erkuran Yilmaz C, Granger DN. Source Department of Molecular and Cellular Physiology, Louisiana State University Health Science Center, Shreveport, LA, USA. dgrang@lsuhsc.edu. Abstract ABSTRACT: BACKGROUND-: Although the therapeutic potential of bone marrow-derived stromal…

Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain.

J Cereb Blood Flow Metab. 2011 Jan;31(1):235-42. Epub 2010 Jun 9. Cell number and timing of transplantation determine survival of human neural stem cell grafts in stroke-damaged rat brain. Darsalia V, Allison SJ, Cusulin C, Monni E, Kuzdas D, Kallur T, Lindvall O, Kokaia Z. Source Laboratory of Neural Stem Cell Biology and Therapy, University…