Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain.

Neurosurgery. 2009 Oct; 65(4) : 741-53; discussion 753. Environmental cue-dependent dopaminergic neuronal differentiation and functional effect of grafted neuroepithelial stem cells in parkinsonian brain. Mine Y, Hayashi T, Yamada M, Okano H, Kawase T. Department of Neurosurgery, School of Medicine, Keio University, Tokyo, Japan. Erratum in: Neurosurgery. 2009 Dec;65(6):1062. Abstract OBJECTIVE: To physiologically repair damaged…

Cell replacement therapy for Parkinson’s disease

Biochim Biophys Acta. 2009 Jul; 1792(7) : 688-702. Epub 2008 Oct 25. Cell replacement therapy for Parkinson’s disease. Wijeyekoon R, Barker RA. Cambridge Centre for Brain Repair, Forvie Site, Cambridge, UK. Abstract Parkinson’s disease (PD) is a progressive neurodegenerative disorder in which the degeneration of dopaminergic neurons projecting from the substantia nigra to the striatum…

Human stem cells for CNS repair

Cell Tissue Res. 2008 Jan; 331(1) : 301-22. Epub 2007 Sep 28. Human stem cells for CNS repair. Zietlow R, Lane EL, Dunnett SB, Rosser AE. Brain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3US, UK. zietlowr@cf.ac.uk Abstract Although most peripheral tissues have at least a limited ability for self-repair, the central nervous…

Stem cell sources and therapeutic approaches for central nervous system and neural retinal disorders.

Neurosurg Focus. 2008; 24(3-4) : E11. Stem cell sources and therapeutic approaches for central nervous system and neural retinal disorders. Yu D, Silva GA. Department of Bioengineering, University of California, San Diego, USA. Abstract In the past decades, stem cell biology has made a profound impact on our views of mammalian development as well as…

Stem cell-based therapy for Parkinson’s disease.

Ann Med. 2005; 37(7) : 487-98. Stem cell-based therapy for Parkinson’s disease. Correia AS, Anisimov SV, Li JY, Brundin P. Neuronal Survival Unit, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden. Sofia.Correia@med.lu.se Abstract Motor dysfunctions in Parkinson’s disease are considered to be primarily due to the degeneration of dopaminergic neurons in…