Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

Present status and perspectives of stem cell-based therapies for gastrointestinal diseases.

Stem Cell Rev. 2009 Sep;5(3):278-82. Epub 2009 May 27. Present status and perspectives of stem cell-based therapies for gastrointestinal diseases. Yan L, Cai C, Li J, Xu S, Chang Q, Li Y, Wu B. Gastrointestinal Department of Southern Building, PLA general hospital, Beijing, China. Abstract In recent years the interest in stem cell-based therapies for…

Targeting improves MSC treatment of inflammatory bowel disease.

Mol Ther. 2010 Jul;18(7):1365-72. Epub 2010 Apr 13. Targeting improves MSC treatment of inflammatory bowel disease. Ko IK, Kim BG, Awadallah A, Mikulan J, Lin P, Letterio JJ, Dennis JE. Source Department of Orthopedics, Case Western Reserve University, Cleveland, Ohio, USA. Abstract Inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, is an…

Microcirculation and tissue regeneration

Gastroenterology. 2007 Mar;132(3):944-54. Epub 2006 Dec 19. Nonmyeloablative stem cell therapy enhances microcirculation and tissue regeneration in murine inflammatory bowel disease. Khalil PN, Weiler V, Nelson PJ, Khalil MN, Moosmann S, Mutschler WE, Siebeck M, Huss R. Source Department of Surgery, Klinikum Innenstadt, Ludwig-Maximilians-Universität of München, Munich, Germany. philipe.khalil@med.uni-muenchen.de Abstract BACKGROUND AND AIMS: Reduced microcirculation…

Stem cells and complex perianal fistula

Dis Colon Rectum. 2009 Jan;52(1):79-86. Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial. Garcia-Olmo D, Herreros D, Pascual I, Pascual JA, Del-Valle E, Zorrilla J, De-La-Quintana P, Garcia-Arranz M, Pascual M. Source Department of Surgery and Cell Therapy, La Paz University Hospital, Universidad Autónoma de Madrid, Madrid,…

Risk reduction in ulcerative colitis relapse

Eksp Klin Gastroenterol. 2010;(3):5-10. Transplantation of allogeneic mesenchymal stem cells from the bone marrow increases duration of remission and reduces the risk of ulcerative colitis relapse. [Article in Russian] Lazebnik LB, Kniazev OV, Parfenov AI, Ruchkina IN, Rogozina VA, Konopliannikov AG. Abstract The first results of allogeneic mesenchymal stem cells from the bone marrow transplantation…