Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

Autologous stem cell transplantation for severe autoimmune diseases: a 10-year experience.

Ann N Y Acad Sci. 2007 Sep;1110:455-64 Autologous stem cell transplantation for severe autoimmune diseases: a 10-year experience. Authors: Gualandi F, Bruno B, Van Lint MT, Luchetti S, Uccelli A, Capello E, Mancardi GL, Bacigalupo A, Marmont A The first autologous hematopoietic stem cell transplantation in Europe for a patient with severe refractory systemic lupus…

Immunoregulatory effect of bone marrow mesenchymal stem cells on regulatory T cells in patients with systemic lupus erythematosis

Zhonghua Nei Ke Za Zhi. 2007 Dec;46(12):1018-21 Immunoregulatory effect of bone marrow mesenchymal stem cells on regulatory T cells in patients with systemic lupus erythematosis  Authors: Sun Y, Zhang FS, Zhang ZY OBJECTIVE: To study the in vitro modulation of autogeneic and allogenic regulatory T lymphocytes proliferation by bone marrow mesenchymal stem cells (MSCs) in…

Hematopoietic stem cell transplantation in autoimmune diseases

Medicina (B Aires). 2008;68(2):153-63 Hematopoietic stem cell transplantation in autoimmune diseases Authors: Albarracín F, López Meiller MJ, Naswetter G, Longoni H Transplantation of hematopoietic stem cells, which are capable of self renewal and reconstitution of all types of blood cells, can be a treatment for numerous potential lethal diseases, including leukemias and lymphomas. It may…

Autoimmune disease: is it a disorder of the microenvironment?

Immunol Res. 2008;41(1):79-86 Autoimmune disease: is it a disorder of the microenvironment? Authors: El-Badri NS, Hakki A, Ferrari A, Shamekh R, Good RA Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease that involves several vital organs including the cardiovascular system, joints, and kidneys. The pathology is characterized by accumulation of autoreactive lymphocytes that…

Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells.

Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Yoshimura K, Sato K, Aoi N, Kurita M, Inoue K, Suga H, Eto H, Kato H, Hirohi T, Harii K. Source Department of Plastic Surgery, University of Tokyo School of Medicine, Tokyo, Japan. yoshimura-pla@h.u-tokyo.ac.jp Abstract BACKGROUND: Lipoinjection is a promising treatment, but…

Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice.

Cell Mol Immunol. 2008 Dec;5(6):417-24. Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice. Zhou K, Zhang H, Jin O, Feng X, Yao G, Hou Y, Sun L. Source Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu, China. Abstract Recent evidence…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Bone Marrow Transplant. 2009 Jun;43(11):821-8. Epub 2009 Mar 23. Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune…