Microcirculation and tissue regeneration

Gastroenterology. 2007 Mar;132(3):944-54. Epub 2006 Dec 19. Nonmyeloablative stem cell therapy enhances microcirculation and tissue regeneration in murine inflammatory bowel disease. Khalil PN, Weiler V, Nelson PJ, Khalil MN, Moosmann S, Mutschler WE, Siebeck M, Huss R. Source Department of Surgery, Klinikum Innenstadt, Ludwig-Maximilians-Universität of München, Munich, Germany. philipe.khalil@med.uni-muenchen.de Abstract BACKGROUND AND AIMS: Reduced microcirculation…

Stem cells and complex perianal fistula

Dis Colon Rectum. 2009 Jan;52(1):79-86. Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial. Garcia-Olmo D, Herreros D, Pascual I, Pascual JA, Del-Valle E, Zorrilla J, De-La-Quintana P, Garcia-Arranz M, Pascual M. Source Department of Surgery and Cell Therapy, La Paz University Hospital, Universidad Autónoma de Madrid, Madrid,…

Risk reduction in ulcerative colitis relapse

Eksp Klin Gastroenterol. 2010;(3):5-10. Transplantation of allogeneic mesenchymal stem cells from the bone marrow increases duration of remission and reduces the risk of ulcerative colitis relapse. [Article in Russian] Lazebnik LB, Kniazev OV, Parfenov AI, Ruchkina IN, Rogozina VA, Konopliannikov AG. Abstract The first results of allogeneic mesenchymal stem cells from the bone marrow transplantation…

Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn’s disease.

Gut. 2011 Jun;60(6):788-98. Epub 2011 Jan 21. Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn’s disease. Ciccocioppo R, Bernardo ME, Sgarella A, Maccario R, Avanzini MA, Ubezio C, Minelli A, Alvisi C, Vanoli A, Calliada F, Dionigi P, Perotti C, Locatelli F, Corazza GR. Source Clinica Medica I, Fondazione IRCCS Policlinico…

Crohn’s Disease and stem cells

Front Biosci (Schol Ed). 2010 Jun 1;2:993-1008. Stem cells as potential therapeutic targets for inflammatory bowel disease. Singh UP, Singh NP, Singh B, Mishra MK, Nagarkatti M, Nagarkatti PS, Singh SR. Source Pathology and Microbiology and Immunology, School of Medicine, University of South Carolina, Columbia, SC 29208, USA. Abstract The incidence and prevalence of Crohn’s…

Auto-Immune disease & stem cells transplant

2010 Jan;16(1 Suppl):S48-56 Hematopoietic cell transplantation for autoimmune disease: updates from Europe and the United States. Sullivan KM, Muraro P, Tyndall A Abstract Considerable advances have been made in our understanding of the immunobiology of autoimmune disease and its treatment with hematopoietic cell transplantation (HCT). In autoimmune disorders, the reconstituted immune system following lymphoablation and…

Adult stem cell transplantation in autoimmune disease

2009 Jul;16(4):285-91 Adult stem cell transplantation in autoimmune disease. Tyndall A, Gratwohl A PURPOSE OF REVIEW: This review presents the recent results of a decade’s experience with hematopoietic stem cell transplantation for treating severe autoimmune disease, with special reference to new insights into pathophysiology. In addition, the newly evolving field of mesenchymal stem cell therapy…