Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.

Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Source Inserm U697, Paris, France. Abstract Mesenchymal stem cells (MSCs) are multipotent…

Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens.

Curr Dir Autoimmun. 2008;10:258-79 Scleroderma. Authors: Gilliam AC The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors…

Auto-Immune disease & stem cells transplant

2010 Jan;16(1 Suppl):S48-56 Hematopoietic cell transplantation for autoimmune disease: updates from Europe and the United States. Sullivan KM, Muraro P, Tyndall A Abstract Considerable advances have been made in our understanding of the immunobiology of autoimmune disease and its treatment with hematopoietic cell transplantation (HCT). In autoimmune disorders, the reconstituted immune system following lymphoablation and…

Adult stem cell transplantation in autoimmune disease

2009 Jul;16(4):285-91 Adult stem cell transplantation in autoimmune disease. Tyndall A, Gratwohl A PURPOSE OF REVIEW: This review presents the recent results of a decade’s experience with hematopoietic stem cell transplantation for treating severe autoimmune disease, with special reference to new insights into pathophysiology. In addition, the newly evolving field of mesenchymal stem cell therapy…

Vascular disease in scleroderma

2008 Feb;34(1):73-9; vi. Vascular disease in scleroderma: angiogenesis and vascular repair Mulligan-Kehoe MJ, Simons M. Angiogenesis Research Center, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Borwell 530 E, 1 Medical Center Drive, Lebanon, NH 03756, USA. Abstract Vascular abnormalities are one of the primary pathologic components of scleroderma. An early vascular indicator is aberrant nail fold…