Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up.

Cytotherapy. 2009;11(1):18-25. Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up. Deda H, Inci MC, Kürekçi AE, Sav A, Kayihan K, Ozgün E, Ustünsoy GE, Kocabay S. Department of Neurosurgery and Neurology, Akay Hospital, Ankara, Turkey. halukdeda@gmail.com Comment in: Cytotherapy. 2009;11(2):256-7; author reply 258. Abstract BACKGROUND: Amyotrophic…

Adult stem cells for the treatment of neurological disease.

Methods Mol Biol. 2009;549:17-32. Adult stem cells for the treatment of neurological disease. Rice CM, Scolding NJ. University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK. Abstract The characteristic CNS responses to injury including increased cell production and attempts at regenerative repair – implicitly predicted where not directly demonstrated by Cajal, but only…

Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.

Curr Stem Cell Res Ther. 2009 Sep;4(3):178-99. Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis. Thonhoff JR, Ojeda L, Wu P. Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-0620, USA. Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease caused by the selective loss of both…

Stem cells in amyotrophic lateral sclerosis: state of the art.

Expert Opin Biol Ther. 2009 Oct;9(10):1245-58. Stem cells in amyotrophic lateral sclerosis: state of the art. Mazzini L, Vercelli A, Ferrero I, Mareschi K, Boido M, Servo S, Oggioni GD, Testa L, Monaco F, Fagioli F. Eastern Piedmont University, Maggiore della Carità Hospital, ALS Centre, Department of Neurology, Corso Mazzini 18, Novara 28100, Italy. mazzini.l@libero.it…

Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis.

Brain Res. 2009 Nov 3;1296:216-24. Epub 2009 Aug 15. Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis. Ohnishi S, Ito H, Suzuki Y, Adachi Y, Wate R, Zhang J, Nakano S, Kusaka H, Ikehara S. Department of Neurology, Kansai…

Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients.

Cytotherapy. 2009;11(1):26-34. Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients. Martinez HR, Gonzalez-Garza MT, Moreno-Cuevas JE, Caro E, Gutierrez-Jimenez E, Segura JJ. Servicio de Neurologia, Hospital Universitario UANL, Monterrey, Mexico. drhectormtz@yahoo.com Abstract BACKGROUND AIMS: Amyotrophic lateral sclerosis (ALS) is characterized by the selective death of motor neurons. CD133(+) stem cells are…

Advances in stem cell research for Amyotrophic Lateral Sclerosis.

Curr Opin Biotechnol. 2009 Oct;20(5):545-51. Epub 2009 Oct 12. Advances in stem cell research for Amyotrophic Lateral Sclerosis. Papadeas ST, Maragakis NJ. Johns Hopkins University, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD 21287, USA. Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized primarily by motor neuron loss in the motor cortex and…

Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice.

Neurosci Lett. 2010 Jan 14;468(3):190-4. Epub 2009 Oct 29. Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice. Kim H, Kim HY, Choi MR, Hwang S, Nam KH, Kim HC, Han JS, Kim KS, Yoon HS, Kim SH. Department of Neurology, College of Medicine, Hanyang University, #17 Haengdang-dong, Seongdong-gu,…

Selection of optimal passage of bone marrow-derived mesenchymal stem cells for stem cell therapy in patients with amyotrophic lateral sclerosis.

Neurosci Lett. 2010 Mar 19;472(2):94-8. Epub 2010 Feb 1. Selection of optimal passage of bone marrow-derived mesenchymal stem cells for stem cell therapy in patients with amyotrophic lateral sclerosis. Choi MR, Kim HY, Park JY, Lee TY, Baik CS, Chai YG, Jung KH, Park KS, Roh W, Kim KS, Kim SH. Division of Molecular and…

Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis.

Cell Transplant. 2010;19(5):537-48. Epub 2010 Mar 26. Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis. Mitrecić D, Nicaise C, Gajović S, Pochet R. Université Libre de Bruxelles, Brussels, Belgium. dominic@mef.hr Abstract The transplantation of neural stem cells (NSCs) is a challenging therapeutic strategy for the…