Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial.

Exp Neurol. 2010 May;223(1):229-37. Epub 2009 Aug 13. Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial. Mazzini L, Ferrero I, Luparello V, Rustichelli D, Gunetti M, Mareschi K, Testa L, Stecco A, Tarletti R, Miglioretti M, Fava E, Nasuelli N, Cisari C, Massara M, Vercelli R, Oggioni GD, Carriero A,…

Stem cells in amyotrophic lateral sclerosis: motor neuron protection or replacement?

CNS Neurol Disord Drug Targets. 2010 Jul;9(3):314-24. Stem cells in amyotrophic lateral sclerosis: motor neuron protection or replacement? Silani V, Calzarossa C, Cova L, Ticozzi N. Department of Neurology and Laboratory of Neuroscience, “Dino Ferrari” Center, Università degli Studi di Milano-IRCCS Istituto Auxologico Italiano, Milano, Italy. vincenzo@silani.com Abstract Given the lack of effective drug treatments…

Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells.

Neuropathol Appl Neurobiol. 2010 Sep 15. doi: 10.1111/j.1365-2990.2010.01124.x. [Epub ahead of print] Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells. Nicaise C, Mitrecic D, Pochet R. Laboratory of Histology, Neuroanatomy and Neuropathology, Université Libre de Bruxelles, Brussels, Belgium Laboratory for Neurogenetics and…

Stem cells and the ALS neurologist.

Amyotroph Lateral Scler. 2010 Oct;11(5):417-23. Stem cells and the ALS neurologist. Maragakis NJ. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. nmaragak@jhmi.edu Abstract Stem cells have captured the imagination of people with ALS. The potential promise of neuronal replacement and regeneration, as well as replacement and regeneration of other neural…

Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosis.

Hum Mol Genet. 2010 Oct 1;19(19):3782-96 Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosis. Corti S, Nizzardo M, Nardini M, Donadoni C, Salani S, Simone C, Falcone M, Riboldi G, Govoni A, Bresolin N, Comi GP Abstract Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, neurodegenerative disease…

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.

Arch Neurol. 2010 Oct;67(10):1187-94. Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis. Karussis D, Karageorgiou C, Vaknin-Dembinsky A, Gowda-Kurkalli B, Gomori JM, Kassis I, Bulte JW, Petrou P, Ben-Hur T, Abramsky O, Slavin S. Department of Neurology, Hadassah-Hebrew University Hospital, Ein Karem, Jerusalem IL-91120, Israel.…

Consistent bone marrow-derived cell mobilization following repeated short courses of granulocyte-colony-stimulating factor in patients with amyotrophic lateral sclerosis: results from a multicenter prospective trial.

Cytotherapy. 2010;12(1):50-9. Consistent bone marrow-derived cell mobilization following repeated short courses of granulocyte-colony-stimulating factor in patients with amyotrophic lateral sclerosis: results from a multicenter prospective trial. Tarella C, Rutella S, Gualandi F, Melazzini M, Scimè R, Petrini M, Moglia C, Ulla M, Omedé P, Bella VL, Corbo M, Silani V, Siciliano G, Mora G, Caponnetto…

Research advances in amyotrophic lateral sclerosis, 2009 to 2010.

Curr Neurol Neurosci Rep. 2011 Feb;11(1):67-77. Research advances in amyotrophic lateral sclerosis, 2009 to 2010. Traub R, Mitsumoto H, Rowland LP. Eleanor and Lou Gehrig MDA/ALS Research Center, Neurological Institute, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA. rt2238@columbia.edu Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of upper…

Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy.

Cytotherapy. 2011 Jan 13. [Epub ahead of print] Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. Ikegame Y, Yamashita K, Hayashi SI, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura SI, Iwama T. Source Department of Neurosurgery, Gifu University Graduate School…

A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke.

Cells. 2010 Jun;28(6):1099-106 A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke. • Lee JS, Hong JM, Moon GJ, Lee PH, Ahn YH, Bang OY, • We previously evaluated the short-term follow-up preliminary data of mesenchymal stem cells (MSCs) transplantation in patients with ischemic stroke. The present study…