Stem cells and neurological diseases.

Gene Ther. 2010 Sep 30. [Epub ahead of print] Progress and prospects: stem cells and neurological diseases. Gögel S, Gubernator M, Minger SL. Wolfson Centre for Age-Related Diseases, Guy’s Campus, King’s College London, London, UK. Abstract The central nervous system has limited capacity of regenerating lost tissue in slowly progressive, degenerative neurological conditions such as…

Dopaminergic neuronal cells in Parkinson’s model rats.

Neurosurg. 2010 Sep; 113(3) : 648-55. Skin-derived precursors differentiating into dopaminergic neuronal cells in the brains of Parkinson disease model rats. Higashida T, Jitsuki S, Kubo A, Mitsushima D, Kamiya Y, Kanno H. Department of Neurosurgery, Yokohama City University, School of Medicine, Yokohama, Kanagawa, Japan. tets018@gmail.com Abstract OBJECT: In the authors’ previous study, they observed…

Stem cells promote recovery in a rat model of Parkinson’s disease.

J Neurosci Res. 2010 Sep; 88(12) : 2669-81. Glial cell line-derived neurotrophic factor-secreting genetically modified human bone marrow-derived mesenchymal stem cells promote recovery in a rat model of Parkinson’s disease. Glavaski-Joksimovic A, Virag T, Mangatu TA, McGrogan M, Wang XS, Bohn MC. Department of Pediatrics, Neurobiology Program, Children’s Memorial Research Center, Feinberg School of Medicine,…

Translation of stem cell therapy for neurological diseases.

Transl Res. 2010 Sep; 156(3) : 155-60. Epub 2010 Jul 23. Translation of stem cell therapy for neurological diseases. Schwarz SC, Schwarz J. Department of Neurology, University of Leipzig, Leipzig, Germany. Abstract “Regenerative medicine” hopefully will provide novel therapies for diseases that remain without effective therapy. This development is also true for most neurodegenerative disorders…

Cell transplantation in Parkinson’s disease.

Curr Opin Neurol. 2010 Aug; 23(4) : 426-32. Cell transplantation in Parkinson’s disease: problems and perspectives. Allan LE, Petit GH, Brundin P. Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden. Abstract PURPOSE OF REVIEW: We review recent experiments conducted using embryonic tissue and stem cell transplants in experimental models of Parkinson’s disease. We…

Cripto blocking Peptides and Parkinson’s

Stem Cells. 2010 Aug; 28(8) : 1326-37. A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson’s disease. Lonardo E, Parish CL, Ponticelli S, Marasco D, Ribeiro D, Ruvo M, De Falco S, Arenas E, Minchiotti G. Stem Cell Fate…

Dopaminergic neurons.

Stem Cells Dev. 2010 Jul; 19(7) : 1017-23. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats. Cai J, Yang M, Poremsky E, Kidd S, Schneider JS, Iacovitti L. Farber Institute for Neurosciences, Department of Neurology, Thomas Jefferson University , Philadelphia, PA 19107, USA. Abstract Cell replacement therapy could…