Article Citations

Nguyen A, Guo J, Banyard DA, Fadavi D, Toranto JD, Wirth GA, Paydar KZ, Evans GR, Widgerow AD. Stromal vascular fraction: A regenerative reality? Part 1: Current concepts and review of the literature. J Plast Reconstr Aesthet Surg. 2016 Feb;69(2):170-9. doi: 10.1016/j.bjps.2015.10.015. Epub 2015 Oct 31. Click here to purchase article   Guo J, Nguyen A, Banyard DA, Fadavi D, Toranto JD, Wirth GA, Paydar KZ, Evans GR, Widgerow AD. Stromal vascular fraction: A regenerative reality? Part 2: Mechanisms of regenerative action. J Plast Reconstr Aesthet Surg. 2016 Feb;69(2):180-8. doi:…

Clinical outcome of autologous peripheral blood stem cell transplantation in opticospinal and conventional forms of secondary progressive multiple sclerosis in a Chinese population.

Xu J1, Ji BX, Su L, Dong HQ, Sun WL, Wan SG, Liu YO, Zhang P, Liu CY. Author information Abstract To evaluate clinical outcomes of autologous peripheral blood stem cell transplantation (APBCST) between opticospinal multiple sclerosis (OSMS) and conventional multiple sclerosis (CMS) during disease progressive stage in a Chinese population. Thirty-six secondary progressive MS patients, among whom 21 were with OSMS and 15 with…

Human umbilical cord mesenchymal stem cell therapy on neuromyelitis optica.

Lu Z1, Ye D, Qian L, Zhu L, Wang C, Guan D, Zhang X, Xu Y. Author information Abstract Stem cell transplantation is a promising therapy for neuromyelitis optica (NMO). Among stem cell varieties, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) possess many advantages, add a differential potential into neural cells, secrete a set of trophic factors and cytokines, regulate immunological function, and have therapeutic potential for neurological…

A review of the potential to restore vision with stem cells.

Mooney I, LaMotte J. Source Southern California College of Optometry, Fullerton, California 92831, USA. Abstract Vision research involving stem cells is a rapidly evolving field. Animal experiments have shown that in response to environmental cues, stem cells can repopulate damaged retinas, regrow neuronal axons, repair higher cortical pathways, and restore pupil reflexes, light responses and basic…

Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve.

Dahlmann-Noor A, Vijay S, Jayaram H, Limb A, Khaw PT. Source UCL Partners AHSC, London, United Kingdom. Abstract The 3 most common causes of visual impairment and legal blindness in developed countries (age-related macular degeneration, glaucoma, and diabetic retinopathy) share 1 end point: the loss of neural cells of the eye. Although recent treatment advances can slow down the progression of…

Stem cell-based therapeutic applications in retinal degenerative diseases.

Huang Y, Enzmann V, Ildstad ST. Source Institute for Cellular Therapeutics, University of Louisville, 570 S. Preston Street, Suite 404, Louisville, KY 40202-1760, USA. Abstract Retinal degenerative diseases that target photoreceptors or the adjacent retinal pigment epithelium (RPE) affect millions of people worldwide. Retinaldegeneration (RD) is found in many different forms of retinal diseases including retinitis pigmentosa (RP), age-related macular degeneration (AMD), diabetic retinopathy, cataracts, and glaucoma.…

Retinal incorporation and differentiation of mesenchymal stem cells intravitreally injected in the injured retina of rats.

Castanheira P, Torquetti L, Nehemy MB, Goes AM. Source Department of Biochemistry, Biological Sciences Institute, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. Abstract PURPOSE: To evaluate the pattern of retinal integration and differentiation of mesenchymal stem cells (MSCs) injected into the vitreous cavity of rat eyes with retinal injury. METHODS: Adult rat retinas…

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transection.

Levkovitch-Verbin H, Sadan O, Vander S, Rosner M, Barhum Y, Melamed E, Offen D, Melamed S. Source Goldschleger Eye Institute, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Israel. hani.verbin@sheba.health.gov.il Abstract PURPOSE: To evaluate the neuroprotective effect of intravitreal injections of neurotrophic factors secreting mesenchymal stem cells (NTF-SCs) on the survival of…

Intravitreal autologous bone marrow-derived mononuclear cell transplantation: a feasibility report.

Jonas JB, Witzens-Harig M, Arseniev L, Ho AD. Source Department of Ophthalmology, Medical Faculty Mannheim, Ruprecht-Karls-University, Heidelberg, Germany. Jost.Jonas@augen.ma.uni-heidelberg.de Abstract PURPOSE: To report on the feasibility and safety of an intravitreal injection of mononuclear cells derived from autologous bone marrow. METHODS: A 43-year-old patient with very advanced atrophy of the retina and optic nerve caused…