Applications in cartilage repair and osteoarthritis therapy

Histol Histopathol. 2009 Mar; 24(3) : 347-66. Mesenchymal stem cells in connective tissue engineering and regenerative medicine: applications in cartilage repair and osteoarthritis therapy. Mobasheri A, Csaki C, Clutterbuck AL, Rahmanzadeh M, Shakibaei M. Division of Veterinary Medicine, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, United Kingdom. ali.mobasheri@nottingham.ac.uk Abstract…

Mesenchymal stem cells in arthritic diseases.

Arthritis Res Ther. 2008; 10(5) : 223. Epub 2008 Oct 10. Mesenchymal stem cells in arthritic diseases. Chen FH, Tuan RS. Cartilage Biology and Orthopaedics Branch, National Institute of Arthritis, and Musculoskeletal and Skin Diseases, National Institutes of Health, 50 South Dr, Bethesda, MD 20892, USA. chenf1@mail.nih.gov Abstract Mesenchymal stem cells (MSCs), the nonhematopoietic progenitor…

Mesenchymal stem cell-based repair of articular cartilage.

J Artif Organs. 2008 Jun; 31(6) : 480-9 Mesenchymal stem cell-based repair of articular cartilage with polyglycolic acidhydroxyapatite biphasic scaffold. Zhou XZ, Leung VY, Dong QR, Cheung KM, Chan D, Lu WW Abstract This study investigates the capacity of a composite scaffold composed of polyglycolic acid-hydroxyapatite (PGA-HA) and autologous mesenchymal stem cells (MSCs) to promote…

Interactive effects of growth factors

Biotechnol Appl Biochem. 2008 Mar; 49(Pt 3) : 185-94. Interactive effects of growth factors and three-dimensional scaffolds on multipotent mesenchymal stromal cells. Heckmann L, Fiedler J, Mattes T, Dauner M, Brenner RE Abstract The creation of tissue-engineered constructs with autologous cells is a central goal in regenerative medicine. With respect to ligament replacement, we have…

Tissue engineering versus regenerative medicine

J Cell Physiol. 2007 Nov; 213(2) : 341-7. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. Caplan AI. Skeletal Research Center, Department of Biology, Case Western Reserve University, Cleveland, Ohio, USA. arnold.caplan@case.edu Abstract Adult mesenchymal stem cells (MSCs) can be isolated from bone marrow or marrow aspirates and because they are culture-dish adherent,…

Regenerative medicine in orthopaedic surgery

J Orthop Res. 2007 Oct; 25(10) : 1261-8. Regenerative medicine in orthopaedic surgery. Corsi KA, Schwarz EM, Mooney DJ, Huard J: Stem Cell Research Center, Children’s Hospital of Pittsburgh, 4100 Rangos Research Center, 3460 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA. Abstract Regenerative medicine holds great promise for orthopaedic surgery. As surgeons continue to face challenges…