Intra-articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial

Intra-articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial Chris Hyunchul Jo1, Young Gil Lee1, Won Hyoung Shin1, Hyang Kim1, Jee Won Chai2, Eui Cheol Jeong3, Ji Eun Kim4, Hackjoon Shim5, Ji Sun Shin1, Il Seob Shin6, Jeong Chan Ra6, Sohee Oh7, and Kang Sup Yoon1* 1Department of Orthopedic Surgery,…

Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy: A Randomized, Double-Blind, Controlled Study.

Vangeness article   J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. doi: 10.2106/JBJS.M.00058. Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy: A Randomized, Double-Blind, Controlled Study. Vangsness CT Jr1, Farr J 2nd2, Boyd J3, Dellaero DT4, Mills CR5, Leroux-Williams M5. Author information 1University of Southern California Orthopaedic…

Application of biologics in the treatment of the rotator cuff, meniscus, cartilage, and osteoarthritis.

  J Am Acad Orthop Surg. 2014 Feb;22(2):68-79. doi: 10.5435/JAAOS-22-02-68. Application of biologics in the treatment of the rotator cuff, meniscus, cartilage, and osteoarthritis. Anz AW, Hackel JG, Nilssen EC, Andrews JR. Abstract Advances in our knowledge of cell signaling and biology have led to the development of products that may guide the healing/regenerative process.…

Safety reporting on implantation of autologous adipose tissue-derived stem cells with platelet-rich plasma into human articular joints.

BMC Musculoskelet Disord. 2013 Dec 1;14:337. doi: 10.1186/1471-2474-14-337. Safety reporting on implantation of autologous adipose tissue-derived stem cells with platelet-rich plasma into human articular joints. Pak J, Chang JJ, Lee JH, Lee SH. Author information Abstract BACKGROUND: Adipose tissue-derived stem cells (ADSCs), a type of mesenchymal stem cells (MSCs), have great potential as therapeutic agents in regenerative medicine. Numerous…

Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series.

J Med Case Rep. 2011 Jul 7;5:296. doi: 10.1186/1752-1947-5-296. Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series. Pak J. Author information Miplant Stems Clinic, 32-3 Chungdam-Dong, Gangnam-Gu, Fourth Floor, Seoul, Korea. jaewoopak@paksmedical.com. Abstract INTRODUCTION: This is a series of clinical case reports demonstrating…

Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose-tissue-derived stem cells: a case series

Journal of Medical Case Reports 2011, 5:296 doi:10.1186/1752-1947-5-296 The electronic version of this article is the complete one and can be found online at: http://www.jmedicalcasereports.com/content/5/1/296 Received: 11 October 2010 Accepted: 7 July 2011 Published: 7 July 2011 © 2011 Pak; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of…

Mesenchymal stem cells in tissue engineering

Biomed Mater Res A. 2010 Sep 15; 94(4) : 1150-61. Role of mesenchymal stem cells in tissue engineering of meniscus. Zellner J, Mueller M, Berner A, Dienstknecht T, Kujat R, Nerlich M, Hennemann B, Koller M, Prantl L, Angele M, Angele P. Department of Trauma Surgery, University Hospital of Regensburg, Regensburg, Germany. johannes.zellner@klinik.uni-regensburg.de Abstract Tissue…