Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology.

Hematology. 2007 Jun;12(3):179-91 Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology. Authors: Kapoor S, Wilson AG, Sharrack B, Lobo A, Akil M, Sun L, Dalley CD, Snowden JA The concept of haemopoietic stem cell transplantation (HSCT) to treat severe autoimmune diseases has been around for several…

The use of stem cells for the treatment of autoimmune diseases.

Braz J Med Biol Res. 2007 Dec;40(12):1579-97 The use of stem cells for the treatment of autoimmune diseases. Authors: Rosa SB, Voltarelli JC, Chies JA, Pranke P Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to…

Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases.

Haematologica. 2010 Feb;95(2):284-92 Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Authors: Farge D, Labopin M, Tyndall A, Fassas A, Mancardi GL, Van Laar J, Ouyang J, Kozak T, Moore J, Kötter I, Chesnel…

Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease.

Nat Clin Pract Rheumatol. 2008 Apr;4(4):184-91 Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Authors: Nikolov NP, Pavletic SZ Hematopoietic stem cells (HSCs) have the capacity for self-renewal and the potential to differentiate into all types of hematopoietic and immune system cells. These features have been successfully used to treat a multitude of…

Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.

Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Source Inserm U697, Paris, France. Abstract Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as…

Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

Hemopoietic progenitor cells and bone marrow stromal cells in patients with autoimmune hepatitis type 1 and primary biliary cirrhosis.

J Hepatol. 2003 Nov;39(5):679-85. Hemopoietic progenitor cells and bone marrow stromal cells in patients with autoimmune hepatitis type 1 and primary biliary cirrhosis. Kyriakou DS, Alexandrakis MG, Zachou K, Passam F, Stathakis NE, Dalekos GN. Source Hematology Department, University Hospital of Larisa, University of Thessaly, PO BOX 1425, Larisa, Greece. Abstract BACKGROUND/AIMS: Autologous hematopoietic stem…

Current and future treatments of autoimmune hepatitis.

Expert Rev Gastroenterol Hepatol. 2009 Jun;3(3):269-91. Current and future treatments of autoimmune hepatitis. Czaja AJ. Source Mayo Clinic College of Medicine, Rochester, MN 55905, USA. czaja.albert@mayo.edu Abstract Corticosteroid therapy induces clinical, laboratory and histological improvements in 80% of patients with autoimmune hepatitis. Prednisone, alone or at a lower dose in combination with azathioprine, increases the…