The use of stem cells for the treatment of autoimmune diseases.

Braz J Med Biol Res. 2007 Dec;40(12):1579-97 The use of stem cells for the treatment of autoimmune diseases. Authors: Rosa SB, Voltarelli JC, Chies JA, Pranke P Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to…

Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases.

Haematologica. 2010 Feb;95(2):284-92 Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Authors: Farge D, Labopin M, Tyndall A, Fassas A, Mancardi GL, Van Laar J, Ouyang J, Kozak T, Moore J, Kötter I, Chesnel…

Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease.

Nat Clin Pract Rheumatol. 2008 Apr;4(4):184-91 Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Authors: Nikolov NP, Pavletic SZ Hematopoietic stem cells (HSCs) have the capacity for self-renewal and the potential to differentiate into all types of hematopoietic and immune system cells. These features have been successfully used to treat a multitude of…

Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.

Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Source Inserm U697, Paris, France. Abstract Mesenchymal stem cells (MSCs) are multipotent…

Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens.

Curr Dir Autoimmun. 2008;10:258-79 Scleroderma. Authors: Gilliam AC The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors…

Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis.

Cell Transplant. 2010 Aug 18; Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis. Authors: Chang JW, Hung SP, Wu HH, Wu WM, Yang AH, Tsai HL, Yang LY, Lee OK Msenchymal stem cells (MSCs) have been shown to possess immuno-modulatory properties. Systemic lupus erythematosus is an autoimmune disease which…

ReMobilization, harvesting and selection of peripheral blood stem cells in patients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation.

Bone Marrow Transplant. 2007 Mar;39(6):317-29 ReMobilization, harvesting and selection of peripheral blood stem cells in patients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation. Authors: Statkute L, Verda L, Oyama Y, Traynor A, Villa M, Shook T, Clifton R, Jovanovic B, Satkus J, Loh Y, Quigley K, Yaung K, Gonda E, Krosnjar N, Spahovic…