Cell therapy for autoimmune diseases.

Arthritis Res Ther. 2007;9(2):206 Cell therapy for autoimmune diseases. Authors: Dazzi F, van Laar JM, Cope A, Tyndall A Cell therapy, pioneered for the treatment of malignancies in the form of bone marrow transplantation, has subsequently been tested and successfully employed in autoimmune diseases. Autologous haemopoietic stem cell transplantation (HSCT) has become a curative option…

Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology.

Hematology. 2007 Jun;12(3):179-91 Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology. Authors: Kapoor S, Wilson AG, Sharrack B, Lobo A, Akil M, Sun L, Dalley CD, Snowden JA The concept of haemopoietic stem cell transplantation (HSCT) to treat severe autoimmune diseases has been around for several…

The use of stem cells for the treatment of autoimmune diseases.

Braz J Med Biol Res. 2007 Dec;40(12):1579-97 The use of stem cells for the treatment of autoimmune diseases. Authors: Rosa SB, Voltarelli JC, Chies JA, Pranke P Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to…

Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease.

Nat Clin Pract Rheumatol. 2008 Apr;4(4):184-91 Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Authors: Nikolov NP, Pavletic SZ Hematopoietic stem cells (HSCs) have the capacity for self-renewal and the potential to differentiate into all types of hematopoietic and immune system cells. These features have been successfully used to treat a multitude of…

Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.

Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Source Inserm U697, Paris, France. Abstract Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as…

Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent…

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro…

Diffuse alopecia with stem cell folliculitis: chronic diffuse alopecia areata or a distinct entity?

Am J Dermatopathol. 1999 Feb;21(1):46-50. Diffuse alopecia with stem cell folliculitis: chronic diffuse alopecia areata or a distinct entity? Kossard S. Source Skin and Cancer Foundation, Darlinghurst, NSW, Australia. Abstract A 34-year-old woman presented with an 8-year history of slowly progressive diffuse nonscarring alopecia with loss of hair density. Scalp biopsy specimens showed increased miniaturized…

Potential involvement of the stem cell factor receptor c-kit in alopecia areata and androgenetic alopecia: histopathological, immunohistochemical, and semiquantitative investigations.

Acta Histochem Cytochem. 2010 Feb 27;43(1):9-17. Epub 2010 Feb 26. Potential involvement of the stem cell factor receptor c-kit in alopecia areata and androgenetic alopecia: histopathological, immunohistochemical, and semiquantitative investigations. Ashrafuzzaman M, Yamamoto T, Shibata N, Hirayama TT, Kobayashi M. Source Department of Pathology, Tokyo Women’s Medical University, Tokyo, Japan. drashrafprs@yahoo.com Abstract Alopecia areata (AAR)…

Hair follicle is a target of stress hormone and autoimmune reactions.

J Dermatol Sci. 2010 Nov;60(2):67-73. Epub 2010 Sep 29. Hair follicle is a target of stress hormone and autoimmune reactions. Ito T. Source Department of Dermatology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-1192, Japan. itoutai@hama-med.ac.jp Abstract Interest in the hair follicle (HF) has recently increased, yet the detailed mechanisms of HF function…