Advances in stem cell research for Amyotrophic Lateral Sclerosis.

Curr Opin Biotechnol. 2009 Oct;20(5):545-51. Epub 2009 Oct 12. Advances in stem cell research for Amyotrophic Lateral Sclerosis. Papadeas ST, Maragakis NJ. Johns Hopkins University, 600 N. Wolfe St., Meyer 6-119, Baltimore, MD 21287, USA. Abstract Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized primarily by motor neuron loss in the motor cortex and…

Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice.

Neurosci Lett. 2010 Jan 14;468(3):190-4. Epub 2009 Oct 29. Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice. Kim H, Kim HY, Choi MR, Hwang S, Nam KH, Kim HC, Han JS, Kim KS, Yoon HS, Kim SH. Department of Neurology, College of Medicine, Hanyang University, #17 Haengdang-dong, Seongdong-gu,…

Selection of optimal passage of bone marrow-derived mesenchymal stem cells for stem cell therapy in patients with amyotrophic lateral sclerosis.

Neurosci Lett. 2010 Mar 19;472(2):94-8. Epub 2010 Feb 1. Selection of optimal passage of bone marrow-derived mesenchymal stem cells for stem cell therapy in patients with amyotrophic lateral sclerosis. Choi MR, Kim HY, Park JY, Lee TY, Baik CS, Chai YG, Jung KH, Park KS, Roh W, Kim KS, Kim SH. Division of Molecular and…

Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis.

Cell Transplant. 2010;19(5):537-48. Epub 2010 Mar 26. Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis. Mitrecić D, Nicaise C, Gajović S, Pochet R. Université Libre de Bruxelles, Brussels, Belgium. dominic@mef.hr Abstract The transplantation of neural stem cells (NSCs) is a challenging therapeutic strategy for the…

Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial.

Exp Neurol. 2010 May;223(1):229-37. Epub 2009 Aug 13. Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial. Mazzini L, Ferrero I, Luparello V, Rustichelli D, Gunetti M, Mareschi K, Testa L, Stecco A, Tarletti R, Miglioretti M, Fava E, Nasuelli N, Cisari C, Massara M, Vercelli R, Oggioni GD, Carriero A,…

Stem cells in amyotrophic lateral sclerosis: motor neuron protection or replacement?

CNS Neurol Disord Drug Targets. 2010 Jul;9(3):314-24. Stem cells in amyotrophic lateral sclerosis: motor neuron protection or replacement? Silani V, Calzarossa C, Cova L, Ticozzi N. Department of Neurology and Laboratory of Neuroscience, “Dino Ferrari” Center, Università degli Studi di Milano-IRCCS Istituto Auxologico Italiano, Milano, Italy. vincenzo@silani.com Abstract Given the lack of effective drug treatments…

Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells.

Neuropathol Appl Neurobiol. 2010 Sep 15. doi: 10.1111/j.1365-2990.2010.01124.x. [Epub ahead of print] Brain and spinal cord affected by amyotrophic lateral sclerosis induce differential growth factors expression in rat mesenchymal and neural stem cells. Nicaise C, Mitrecic D, Pochet R. Laboratory of Histology, Neuroanatomy and Neuropathology, Université Libre de Bruxelles, Brussels, Belgium Laboratory for Neurogenetics and…

Stem cells and the ALS neurologist.

Amyotroph Lateral Scler. 2010 Oct;11(5):417-23. Stem cells and the ALS neurologist. Maragakis NJ. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. nmaragak@jhmi.edu Abstract Stem cells have captured the imagination of people with ALS. The potential promise of neuronal replacement and regeneration, as well as replacement and regeneration of other neural…

Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosis.

Hum Mol Genet. 2010 Oct 1;19(19):3782-96 Systemic transplantation of c-kit+ cells exerts a therapeutic effect in a model of amyotrophic lateral sclerosis. Corti S, Nizzardo M, Nardini M, Donadoni C, Salani S, Simone C, Falcone M, Riboldi G, Govoni A, Bresolin N, Comi GP Abstract Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, neurodegenerative disease…

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis.

Arch Neurol. 2010 Oct;67(10):1187-94. Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis. Karussis D, Karageorgiou C, Vaknin-Dembinsky A, Gowda-Kurkalli B, Gomori JM, Kassis I, Bulte JW, Petrou P, Ben-Hur T, Abramsky O, Slavin S. Department of Neurology, Hadassah-Hebrew University Hospital, Ein Karem, Jerusalem IL-91120, Israel.…