Translation of stem cell therapy for neurological diseases.

Transl Res. 2010 Sep; 156(3) : 155-60. Epub 2010 Jul 23. Translation of stem cell therapy for neurological diseases. Schwarz SC, Schwarz J. Department of Neurology, University of Leipzig, Leipzig, Germany. Abstract “Regenerative medicine” hopefully will provide novel therapies for diseases that remain without effective therapy. This development is also true for most neurodegenerative disorders…

Cell transplantation in Parkinson’s disease.

Curr Opin Neurol. 2010 Aug; 23(4) : 426-32. Cell transplantation in Parkinson’s disease: problems and perspectives. Allan LE, Petit GH, Brundin P. Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund, Sweden. Abstract PURPOSE OF REVIEW: We review recent experiments conducted using embryonic tissue and stem cell transplants in experimental models of Parkinson’s disease. We…

Cripto blocking Peptides and Parkinson’s

Stem Cells. 2010 Aug; 28(8) : 1326-37. A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson’s disease. Lonardo E, Parish CL, Ponticelli S, Marasco D, Ribeiro D, Ruvo M, De Falco S, Arenas E, Minchiotti G. Stem Cell Fate…

Dopaminergic neurons.

Stem Cells Dev. 2010 Jul; 19(7) : 1017-23. Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats. Cai J, Yang M, Poremsky E, Kidd S, Schneider JS, Iacovitti L. Farber Institute for Neurosciences, Department of Neurology, Thomas Jefferson University , Philadelphia, PA 19107, USA. Abstract Cell replacement therapy could…

Stem cell replacement therapies for Parkinson’s disease.

Biochem Biophys Res Commun. 2010 May 21; 396(1) : 152-6. Towards stem cell replacement therapies for Parkinson’s disease. Arenas E. Laboratory of Molecular Neurobiology, MBB, Center for Developmental Biology and Regenerative Medicine, Scheelevagen 1, 17177 Stockholm, Sweden. Ernest.Arenas@ki.se Abstract Current therapeutic approaches for Parkinson’s disease (PD) provide symptomatic relief but none of them change the…

Gene therapy in hemiparkinsonian rhesus monkeys:

Cytotherapy. 2010 Apr; 12(2) : 226-37. Gene therapy in hemiparkinsonian rhesus monkeys: long-term survival and behavioral recovery by transplantation of autologous human tyrosine hydroxylase-expressing neural stem cells. Xu Q, Jiang X, Ke Y, Zhang S, Xu R, Zeng Y. Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, Guangzhou, China 510282. Abstract BACKGROUND AIMS: Neural stem…