Stem cells in human neurodegenerative disorders

J Clin Invest. 2010 Jan 4; 120(1): 29-40. d oi: 10.1172/JCI40543. Stem cells in human neurodegenerative disorders–time for clinical translation? Lindvall O, Kokaia Z. Laboratory of Neurogenesis and Cell Therapy, Wallenberg Neuroscience Center, University Hospital, Lund, Sweden. olle.lindvall@med.lu.se Abstract Stem cell-based approaches have received much hype as potential treatments for neurodegenerative disorders. Indeed, transplantation of…

Consequences of germ line stem cells in adult tissues

Ginekol Pol. 2009 Dec; 80(12) : 935-41. Physiological and pathological consequences of a presence of germ line stem cells in adult tissues -[Article in Polish] Ratajczak MZ, Machaliński B, Czajka R, Zuba-Surma E, Poziomkowska-Gesicka I, Słowik-Zyłka D. Zakład Fizjologii Katedry Fizjopatologii Pomorskiej Akademii Medycznej, Szczecin. mzrata01@louisville.edu Abstract Various therapheutic strategies employing stem cells have been…

Cell therapy for Parkinson disease

Rinsho Shinkeigaku. 2009 Nov; 49(11) : 890-2. Cell therapy for Parkinson disease – [Article in Japanese] Muramatsu S. Division of Neurology, Jichi Medical University. Abstract Advances in the field of stem cell research have raised hopes of creating novel cell replacement therapies for Parkinson disease (PD), although double-blinded clinical trials have met with controversial success…

Stem cell therapy for neuronal regeneration

Rinsho Shinkeigaku. 2009 Nov; 49(11) : 834-6. Future of stem cell therapy for neuronal regeneration – [Article in Japanese] Takaha shi J . Department of Biological Repair, Institute for Frontier Medical Sciences, Kyoto University. Abstract Embryonic stem (ES) cells are expected as promising donor cells for cell transplantation therapy. For example, mouse or monkey ES…

Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson’s disease.

J Neuroimmunol. 2009 Nov 30; 216(1-2) : 39-50. Epub 2009 Oct 9. Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson’s disease. Chao YX, He BP, Tay SS. Department of Anatomy, Yong Loo Lin School of Medicine,…

Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule.

Stem Cells. 2009 Nov; 27(11) : 2846-56. Cross-talk between stem cells and the dysfunctional brain is facilitated by manipulating the niche: evidence from an adhesion molecule. Ourednik V, Ourednik J, Xu Y, Zhang Y, Lynch WP, Snyder EY, Schachner M. Department of Biomedical Sciences, VetMed, Iowa State University, Ames, Iowa, USA. Abstract In the injured…