Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy.

2010;260(2):75-82. Mesenchymal stem cells as anti-inflammatories: implications for treatment of Duchenne muscular dystrophy. Ichim TE, Alexandrescu DT, Solano F, Lara F, Campion Rde N, Paris E, Woods EJ, Murphy MP, Dasanu CA, Patel AN, Marleau AM, Leal A, Riordan NH. Medistem Inc., San Diego, CA 92122, USA. Abstract Duchenne muscular dystrophy (DMD) is a lethal…

Inefficient dystrophin expression after cord blood transplantation in Duchenne muscular dystrophy.

2010 Jun;41(6):746-50 Inefficient dystrophin expression after cord blood transplantation in Duchenne muscular dystrophy. Kang PB, Lidov HG, White AJ, Mitchell M, Balasubramanian A, Estrella E, Bennett RR, Darras BT, Shapiro FD, Bambach BJ, Kurtzberg J, Gussoni E, Kunkel LM Abstract We report a boy who received two allogeneic stem cell transplantations from umbilical cord donors…

The potential for treatment of skeletal muscle disorders with adipose-derived stem cells.

2010 Jun;5(2):133-6. The potential for treatment of skeletal muscle disorders with adipose-derived stem cells. Mizuno H. Department of Plastic and Reconstructive Surgery, Nippon Medical School, 1-1-5 Sendagi Bunkyo-ku, Tokyo 1138603, Japan. hmizuno@nms.ac.jp Abstract Stem cell based therapies for the repair and regeneration of various tissues and organs offer a paradigm shift that may provide alternative…

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells.

2010 Jan 4;120(1):11-9. doi: 10.1172/JCI40373. Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells. Tedesco FS, Dellavalle A, Diaz-Manera J, Messina G, Cossu G. Division of Regenerative Medicine, San Raffaele Scientific Institute, 58 via Olgettina, Milan, Italy. Abstract Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to…

Amyotrophic Lateral Sclerosis

2011 Feb; 11(1) : 67-77. Research advances in amyotrophic lateral sclerosis, 2009 to 2010. Traub R, Mitsumoto H, Rowland LP. Eleanor and Lou Gehrig MDA/ALS Research Center, Neurological Institute, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA. rt2238@columbia.edu Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of upper and…

Restoring Endothelial Function

6(4):967-79 Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells. Ning H, Liu G, Lin G, Yang R, Lue TF, Lin CS. Abstract INTRODUCTION: Adipose tissue-derived stem cells (ADSC) could potentially restore endothelial function in vasculogenic erectile dysfunction (ED). The mechanism for ADSC endothelial differentiation remained unidentified. AIM: To test whether ADSC…

Post Radical Prostatectomy

2009 Mar-Apr;(2):46-51 Modern aspects of pathophysiology and prevention of erectile dysfunction and cavernous fibrosis after radical prostatectomy. Veliev EI, Vanin AF, Kotov SV, Shiahlo VK. Abstract Partial denervation of cavernous tissue (CT) during nerve sparing radical prostatectomy (RPE) can cause development of neuropraxy and cavernous fibrosis (CF) resulting in erectile dysfunction (ED) after operation. We…

Treating ED With Stem Cells

6 Suppl 3:320-7 Potential of adipose-derived stem cells for treatment of erectile dysfunction. Lin G, Banie L, Ning H, Bella AJ, Lin CS, Lue TF. Abstract Adipose-derived stem cells (ADSCs) are a somatic stem cell population contained in fat tissue that possess the ability for self-renewal, differentiation into one or more phenotypes, and functional regeneration…

Progress in Gene and Stem Cell Therapy

8(10):1521-38 A review of current progress in gene and stem cell therapy for erectile dysfunction. Gur S, Kadowitz PJ, Hellstrom WJ: Abstract BACKGROUND: Current gene-based strategies for treatment of erectile dysfunction (ED) are based on the nitric oxide (NO)/cGMP system; although growth factors, calcium sensitization, and potassium channel expression have been studied. Initial investigations of…

Repairing Erectile Dysfunction

102(2):220-4; discussion 224. Epub 2008 Jul 1. Human neural crest stem cells transplanted in rat penile corpus cavernosum to repair erectile dysfunction. Song YS, Lee HJ, Park IH, Lim IS, Ku JH, Kim SU OBJECTIVE: To investigate the feasibility of applying neural crest stem cells (NCSCs), with multipotent capacity, to repair injury in the penile…