Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes.

Invest Ophthalmol Vis Sci. 2008 Feb;49(2):732-42. Intravitreal injection of erythropoietin protects both retinal vascular and neuronal cells in early diabetes. Zhang J, Wu Y, Jin Y, Ji F, Sinclair SH, Luo Y, Xu G, Lu L, Dai W, Yanoff M, Li W, Xu GT. Source Laboratory of Clinical Visual Sciences, Institute of Health Sciences, Shanghai…

Stem cell therapy for retinal disease.

Stem cell therapy for retinal disease. Tibbetts MD, Samuel MA, Chang TS, Ho AC. Source Wills Eye Institute Retina Service, Mid Atlantic Retina, Philadelphia, Pennsylvania 19107, USA. michael.tibbetts@gmail.com Abstract PURPOSE OF REVIEW: Stem cell therapy holds great promise for the treatment of retinal diseases. This review summarizes recent advances instem cell biology, outlines ongoing clinical trials and details the obstacles that…

Stem cells: a new paradigm for disease modeling and developing therapies for age-related macular degeneration.

Stem cells: a new paradigm for disease modeling and developing therapies for age-related macular degeneration. Melville H, Carpiniello M, Hollis K, Staffaroni A, Golestaneh N. Abstract Age-related macular degeneration (AMD) is the leading cause of blindness in people over age 55 in the U.S. and the developed world. This condition leads to the progressive impairmen  of central visual acuity. There are significant…

Intravitreal autologous bone marrow-derived mononuclear cell transplantation: a feasibility report.

Intravitreal autologous bone marrow-derived mononuclear cell transplantation: a feasibility report. Acta Ophthalmol. 2008 Mar;86(2):225-6 Authors: Jonas JB, Witzens-Harig M, Arseniev L, Ho AD PURPOSE: To report on the feasibility and safety of an intravitreal injection of mononuclear cells derived from autologous bone marrow. METHODS: A 43-year-old patient with very advanced atrophy of the retina and…

A case of autoimmune-related retinopathy and optic neuropathy syndrome treated by autologous nonmyeloablative hematopoietic stem cell transplantation.

A case of autoimmune-related retinopathy and optic neuropathy syndrome treated by autologous nonmyeloablative hematopoietic stem cell transplantation. J Neuroophthalmol. 2009 Mar;29(1):43-9 Authors: Oyama Y, Burt RK, Thirkill C, Hanna E, Merrill K, Keltner J Autoimmune-related retinopathy and optic neuropathy (ARRON) syndrome is characterized by visual loss and often the presence of antibodies against retinal or…

Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology.

PLoS One. 2010 Feb 15;5(2):e9200. doi: 10.1371/journal.pone.0009200. Non-invasive stem cell therapy in a rat model for retinal degeneration and vascular pathology. Wang S, Lu B, Girman S, Duan J, McFarland T, Zhang QS, Grompe M, Adamus G, Appukuttan B, Lund R. Source Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States of America. wangsha@ohsu.edu Abstract BACKGROUND: Retinitis pigmentosa (RP) is characterized by progressive night blindness, visual field loss, altered vascular permeability and loss of central vision.…

Conditioned medium derived from mesenchymal stem cells culture as a intravesical therapy for cystitis interstitials.

Med Hypotheses. 2014 Mar 4. pii: S0306-9877(14)00098-X. doi: 10.1016/j.mehy.2014.02.027. [Epub ahead of print] Adamowicz J1, Pokrywczyńska M2, Drewa T3. Author information Abstract The treatment of Interstinal Cystitisis (IC) is still challenge for urologist. Available therapies do not result in long-term control of symptoms and do not provide pain relive to patients. Unique abilities of mesenchymal stem cells (MSC)…

Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy: A Randomized, Double-Blind, Controlled Study.

Vangeness article   J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. doi: 10.2106/JBJS.M.00058. Adult Human Mesenchymal Stem Cells Delivered via Intra-Articular Injection to the Knee Following Partial Medial Meniscectomy: A Randomized, Double-Blind, Controlled Study. Vangsness CT Jr1, Farr J 2nd2, Boyd J3, Dellaero DT4, Mills CR5, Leroux-Williams M5. Author information 1University of Southern California Orthopaedic…

Application of biologics in the treatment of the rotator cuff, meniscus, cartilage, and osteoarthritis.

  J Am Acad Orthop Surg. 2014 Feb;22(2):68-79. doi: 10.5435/JAAOS-22-02-68. Application of biologics in the treatment of the rotator cuff, meniscus, cartilage, and osteoarthritis. Anz AW, Hackel JG, Nilssen EC, Andrews JR. Abstract Advances in our knowledge of cell signaling and biology have led to the development of products that may guide the healing/regenerative process.…

Safety reporting on implantation of autologous adipose tissue-derived stem cells with platelet-rich plasma into human articular joints.

BMC Musculoskelet Disord. 2013 Dec 1;14:337. doi: 10.1186/1471-2474-14-337. Safety reporting on implantation of autologous adipose tissue-derived stem cells with platelet-rich plasma into human articular joints. Pak J, Chang JJ, Lee JH, Lee SH. Author information Abstract BACKGROUND: Adipose tissue-derived stem cells (ADSCs), a type of mesenchymal stem cells (MSCs), have great potential as therapeutic agents in regenerative medicine. Numerous…