Gene and stem cell therapy in the treatment of erectile dysfunction and pulmonary hypertension; potential treatments for the common problem of endothelial dysfunction.

Curr Gene Ther. 2007 Apr;7(2):131-53 Gene and stem cell therapy in the treatment of erectile dysfunction and pulmonary hypertension; potential treatments for the common problem of endothelial dysfunction. Nossaman BD, Gur S, Kadowitz PJ. Abstract The endothelium has an important regulatory role in the maintenance of vascular homeostasis, vascular tone, blood flow, and in preserving…

Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction.

  Am J Physiol Heart Circ Physiol. 2007 Mar;292(3):H1278-90. Epub 2006 Oct Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction. Bivalacqua TJ, Deng W, Kendirci M, Usta MF, Robinson C, Taylor BK, Murthy SN, Champion HC, Hellstrom WJ, Kadowitz PJ.   Abstract Mesenchymal stem cells…

Circulating endothelial progenitor cells and endothelial function after chronic Tadalafil treatment in subjects with erectile dysfunction.

Int J Impot Res. 2006 Sep-Oct;18(5):484-8 Circulating endothelial progenitor cells and endothelial function after chronic Tadalafil treatment in subjects with erectile dysfunction. Foresta C, Ferlin A, De Toni L, Lana A, Vinanzi C, Galan A, Caretta N. Abstract We evaluated the effect of a chronic treatment with Tadalafil on progenitor cells (PCs) number and endothelial…

Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.

  J Atheroscler Thromb. 2006 Apr;13(2):77-81. Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. Nakagami H, Morishita R, Maeda K, Kikuchi Y, Ogihara T, Kaneda Y. Abstract Adult stem cells hold great promise for use in tissue repair and regeneration, and the delivery of autologous progenitor cells into ischemic tissue is…

Isolation of primary endothelial and stromal cell cultures of the corpus cavernosum penis for basic research and tissue engineering.

Eur Urol. 2005 May;47(5):710-8; discussion 718-9. Isolation of primary endothelial and stromal cell cultures of the corpus cavernosum penis for basic research and tissue engineering. Pilatz A, Schultheiss D, Gabouev AI, Schlote N, Mertsching H, Jonas U, Stief CG. Abstract OBJECTIVES: Primary cell cultures derived from the corpus cavernosum are frequently used as in vitro…

Endocrine. 2004 Mar-Apr;23(2-3):167-76.

Endocrine. 2004 Mar-Apr;23(2-3):167-76. Therapy of erectile dysfunction: potential future treatments. Gonzalez-Cadavid NF, Rajfer J. Abstract Current research on the development of new medical treatments of erectile dysfunction (ED) fall essentially into two main types of approaches: (1) the traditional strategy based on compounds acting to induce an erection on demand, without modifying the underlying pathologic…