Conditioned medium derived from mesenchymal stem cells culture as a intravesical therapy for cystitis interstitials.

Med Hypotheses. 2014 Mar 4. pii: S0306-9877(14)00098-X. doi: 10.1016/j.mehy.2014.02.027. [Epub ahead of print] Adamowicz J1, Pokrywczyńska M2, Drewa T3. Author information Abstract The treatment of Interstinal Cystitisis (IC) is still challenge for urologist. Available therapies do not result in long-term control of symptoms and do not provide pain relive to patients. Unique abilities of mesenchymal stem cells (MSC)…

INTRAVESICAL PENTOSAN POLYSULFATE ENCAPSULATED IN A LIPOSOME NANOCARRIER FOR INTERSTITIAL CYSTITIS

INTRAVESICAL PENTOSAN POLYSULFATE ENCAPSULATED IN A LIPOSOME NANOCARRIER FOR INTERSTITIAL CYSTITIS Elliot B. Lander MD, Jackie R. See MD INTRODUCTION: There is increasing data supporting glycosaminoglycan barrier restoration therapy for the treatment of Interstitial Cystitis (IC). Pentosan polysulfate (PP) has been used safely and extensively both orally and intravesically for glycosaminoglycan (GAG) barrier restoration therapy.…

AUTOLOGOUS ADIPOSE DERIVED STROMAL VASCULAR FRACTION FOR THE TREATMENT OF INTERSTITIAL CYSTITIS-A PILOT STUDY

AUTOLOGOUS ADIPOSE DERIVED STROMAL VASCULAR FRACTION FOR THE TREATMENT OF INTERSTITIAL CYSTITIS-A PILOT STUDY Elliot B. Lander MD, Mark H. Berman MD, Jackie R. See MD California Stem Cell Treatment Center and Cell Surgical Network INTRODUCTION: We evaluated the safety and efficacy of deployment of SVF Stromal Vascular Fraction (rich in adult mesenchymal stem cells…

Processed lipoaspirate cells for tissue engineering of the lower urinary tract: implications for the treatment of stress urinary incontinence and bladder reconstruction.

8. Urol. 2005 Nov;174(5):2041-5. Processed lipoaspirate cells for tissue engineering of the lower urinary tract: implications for the treatment of stress urinary incontinence and bladder reconstruction. Jack GS, Almeida FG, Zhang R, Alfonso ZC, Zuk PA, Rodríguez LV. Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.…

Cell signaling in interstitial cystitis/painful bladder syndrome.

7. Cell Signal. 2008 Dec;20(12):2174-9. Epub 2008 Jun 19. Cell signaling in interstitial cystitis/painful bladder syndrome. Keay S. Department of Medicine, University of Maryland School of Medicine and Veterans Administration Maryland Health Care System, Baltimore, Maryland, United States. skeay@medicine.umaryland.edu Abstract Evidence for several types of cell signaling abnormalities has been presented for patients with interstitial…

Mesenchymal stem cell recruitment and improved bladder function after bladder outlet obstruction: preliminary data.

J Urol. 2011 Mar;185(3):1132-8. Epub 2011 Jan 21. Mesenchymal stem cell recruitment and improved bladder function after bladder outlet obstruction: preliminary data. Woo LL, Tanaka ST, Anumanthan G, Pope JC 4th, Thomas JC, Adams MC, Brock JW 3rd, Bhowmick NA. Abstract PURPOSE: Mesenchymal stem cells have various therapeutic benefits in various organ injury models. Bladder…

Differentiation of adipose-derived stem cells into contractile smooth muscle cells induced by transforming growth factor-beta1 and bone morphogenetic protein-4.

 Tissue Eng Part A. 2010 Apr;16(4):1201-13. Differentiation of adipose-derived stem cells into contractile smooth muscle cells induced by transforming growth factor-beta1 and bone morphogenetic protein-4. Wang C, Yin S, Cen L, Liu Q, Liu W, Cao Y, Cui L. Department of Plastic and Reconstructive Surgery, Shanghai Jiao Tong University School of Medicine , Shanghai, People’s…

Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):12167-72. Epub 2006 Jul 31. Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells. Rodríguez LV, Alfonso Z, Zhang R, Leung J, Wu B, Ignarro LJ. Department of Urology, University of California School of Medicine, Los Angeles, CA 90024, USA. lrodriguez@mednet.ucla.edu…

The adipose-derived stem cell: looking back and looking ahead.

 MolBiol Cell. 2010 Jun;21(11):1783-7. Epub 2010 Apr 7. The adipose-derived stem cell: looking back and looking ahead. Zuk PA. Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. pzuk@mednet.ucla.edu Abstract In 2002, researchers at UCLA published a manuscript in Molecular Biology of the Cell describing a novel adult…