Jackie R. See M.D., F.A.C.C. is a Board Certified Internist, a Fellow of the American College of Cardiology and pioneer of the specialty of Interventional Cardiology. He founded the teaching program of Interventional Cardiology at the UC Irvine School of Medicine with Jonathan Tobis M.D., F.A.C.C. and Walter Henry M.D., F.A.C.C., prior Dean of the UC Irvine School of Medicine. He is currently the elected Co-President of his alma mater, the UC Irvine College of Medicine Alumni Association. He was born in Missouri and earned his undergraduate degree at UC Riverside. After graduation from medical school and completion of his Internship he served on active duty as a Medical Officer in the United States Navy. This was followed by Residency and Cardiology Fellowship at the Huntington Memorial Hospital and Research Fellowship in Medicine at the Peter Bent Brigham Hospital, Harvard Medical School in Boston. Dr. See has served as Chief of Staff, Vice-Chief of Staff, Chief of Medicine, Chief of Cardiology, Cath Lab Director and other elected Medical Staff positions at Southern California and Nevada Hospitals. He has been on the Medical Staff of the Western Medical Center, Anaheim, from 1983 to the present. Dr. See has published in peer reviewed journals, lectured, invented, patented, developed and marketed enabling technology in digital angiograpthy, angioplasty and ultrasound devices and pharmaceuticals, cholesterol lowering dietary supplements, drug eluting stents, MRI and CT imaging agents, liposomal drug delivery systems, oral vaccine development, stem cell biologic pathway activity, stem cell delivery quantitation devices and Islet Cell Transplantation development. He is a Founding member of the Society of Cardiovascular Computed Tomography, member of the International Liposome Society, Alpha Omega Alpha Society member, member of the Society of Echocardiography and other special interest groups. Dr. See has been a Scientific Advisor for many biotechnology companies and has participated in dozens of clinical trials in cardiovascular disease and diabetes. This has been done while engaged in maintaining an active practice of medicine continually since 1976. He is an active member of the California and Orange County Medical Association. Dr. See, his wife of 42 years, three sons and seven grandchildren share their gratitude of the endless opportunities we enjoy by living in America.

 

Address:
541 Riviera Court
Fullerton, California 92835
(714) 870-7674

E-mail: jrseemd@aol.com

Date and Place of Birth: October 31, 1941, Washington, Missouri

Social Status: Married, 3 Children, 7 Grandchildren

Education:

  • Antelope Valley High School – Lancaster, California – Graduated 1959
  • 1964 B.A. University of California – Riverside, California
  • 1968 M.D. University of California College of Medicine –Irvine, California
  • June 1968 – June 1969 Internship (Rotating Internship Type II), Huntington Memorial Hospital – Pasadena, California
  • January 1972 – February 1973 Residency – Internal Medicine, Huntington Memorial Hospital – Pasadena, California
  • March 1973 – March 1974 – Fellowship – Cardiology, Huntington Memorial Hospital – Pasadena, California
  • July 1974 – July 1975 – Research Fellow in Cardiology, Peter Bent Brigham Hospital Harvard Medical School – Boston, Massachusetts

MILITARY SERVICE:
U.S. Navy Medical Corps – Lieutenant Commander – 1972
Active Duty 1969 – 1972

HONORS AND AWARDS:

  • Honor’s Day Research Award – University of California Irvine, College of Medicine – May 10, 1997
  • Research Associate – Huntington Institute of Applied Medical Research – Summer – 1966
  • Associate Director – Foundation for Cardiovascular Research – 1968 – 1984
  • Fellow American College of Cardiology – 1980
  • Alpha Omega Alpha – Honor Medical Society – Elected Member 1983
  • Director of Research – Foundation for Applied Research Technology – 1980 to Present
  • The New York Academy of Sciences – Elected Active Member 1988

LICENSURE: Licensed in the States of California and Nevada

BOARD CERTIFICATIONS:

  • Diplomat – National Board of Medical Examiners – 1968
  • Diplomat – American Board of Internal Medicine – Certified June 1976

PRESENT MEMBERSHIPS:

  • Fellow, American College of Cardiology:
    • American Heart Association, Clinical Cardiology
    • Council, Basic Cardiovascular Sciences
    • Council, Peripheral Vascular Disease Control
  • New York Academy of Sciences
  • International Liposome Society
  • Society of Cardiovascular CT
  • American Society of Echocardiography
  • American Association for the Advancement of Science
  • Orange County Medical Association

APPOINTMENTS:

  • Assistant Clinical Professor of Medicine – Department of Medicine and Cardiology, School of Medicine, UC Irvine – 1984 – 1997
  • Member Voluntary Faculty Association – UC Irvine School of Medicine – 1997 to 2008
  • University of California, Irvine, School of Medicine, Board Member, Alumni Association – 2007 – present
  • Orange County Medical Association – Orange County Bar Association Liaison Committee – 1985 – 1986
  • Orange County Medical Association Committee on Medical Aspects of Sports and Physical Fitness – 1985 -1986
  • Vice Chief of Staff, Western Medical Center – Anaheim, California – 1986
  • Research Director, Foundation for Applied Research and Technology – 1980 to Present
  • Chairman, Quality Assurance Committee Western Medical Center – 1986
  • Medical Director, Southern California Heart Institute, La Mirada, California – 1986 – 1992
  • Chairman of the Institutional Review Board – Medical Center of La Mirada, La Mirada, California – 1989 – 1992
  • Director, Cardiovascular Medicine Department – Medical Center of La Mirada, La Mirada, California – 1990 – 1991
  • Chief of Staff, Medical Center of La Mirada, La Mirada, California – 1991 – 1992
  • Department of Cardiology – Cardiology Catheterization Committee, Western Medical Center, Anaheim – 1983 – 2012
  • Interventional Cardiologist – Southwest Medical Associates, Las Vegas, Nevada – 1992 – 1995
  • Consulting Interventional Cardiologist – Inland Cardiovascular Medical Group, Riverside, California – 1995 – 2000
  • Private Practice – Consulting Interventional Cardiologist, Fullerton, California – 1976 – Present

AREAS OF RESEARCH INTEREST:

  • Prostaglandins, cardiac effects, and pharmacology
  • Coronary blood flow measurements with digital subtraction angiography
  • 99Tc labeled microspheres study of coronary blood flow and ventricular function
  • Left ventricular function and isotope ventriculography in coronary artery disease
  • Nuclear cardiology
  • Treatment of pericardial inflammation
  • Coronary angioplasty and coronary blood flow measurement for diagnosis
  • PGE-1, myocardial blood flow pre- and postcoronary angioplasty, effects on restenosis
  • Silent ischemia
  • Cholesterol and fat absorption studies
  • Islet cell transplantation
  • Home disease detection kits, HIV and cholesterol
  • Liposomal synthesis
  • Mechanisms of Stem Cell Activity in the heart and lungs
  • Oral vaccine development
  • CT and MRI Imaging Agents

BIBLIOGRAPHY

  • SEE, J.R.: The Relationship of Adrenal Adenomas, the Juxtaglomerular Apparatus, and Hypertension in Humans. Read and abstracted at Honor’s Day, California College of Medicine, May 1967.
  • GIDDINGS, J.A., SEE, J.R., LEWIS, R.D., and COSBY, R.S.: Thromboembolism Following Coronary Angiography. Chest 16: 235-239, 1972.
  • COSBY, R.S., YETT, F.A., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Physician-Computer Interaction as a Clinical Research Technique. JAMA 218: 1548-1551, 1972.
  • COSBY, R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Variant Angina. Case Reports and Critique. American Journal of Medicine 53: 739-742, 1972.
  • COSBY, R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Clinicoarteriographic Correlations in Angina Pectoris with and without Acute Myocardial Infarction. American Journal of Cardiology 30: 472-475, 1972.
  • SEE, J.R., GIDDINGS, J.A., and COSBY, R.S.: Medical Management of Acute Coronary Crisis. Circulation 46: 211-218, 1972.
  • COSBY, R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Myocardial Infarction. Geriatrics 28: 139-142, 1972.
  • GIDDINGS, J.A., SEE, J.R., and COSBY, R.S.: Arteriographic Correlations in Angina, Coronary Insufficiency and Infarction. Clinical Research 21: 419, 1973.
  • GIDDINGS, J.A., SEE, J.R., and COSBY, R.S.: Coronary Arteriography in the Presence of Ventricular Dyskinesia. Clinical Research 21: 419, 1973.
  • SEE, J.R., COSBY, R.S., and GIDDINGS, J.A.: Coronary Angiography of Acute Coronary Insufficiency. Clinical Research 21: 449, 1973.
  • SEE, J.R., COSBY, R.S., and GIDDINGS, J.A.: Coronary Steal Syndrome in the Right and Left Coronary Arteries of the Dog During Acute Coronary Artery Constriction. Clinical Research 21: 449, 1973.
  • COSBY,R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Pathophysiologic Mechanisms in Variant Angina. Chest (editorial) 64: 281-282, 1973.
  • GIDDINGS, J.A., SEE, J.R., and COSBY, R.S.: Hyperkinetic Heart Failure Following Aortic Valve Replacement. Clinical Research 22: 143A, 1973.
  • SEE, J.R., COSBY, R.S., and GIDDINGS, J.A.: Right and Left Coronary Artery Flow and Pressure Dynamics Following Total Occlusion. Clinical Research 22: 152A, 1974.
  • SEE, J.R., GIDDINGS, J.A., and COSBY, R.S.: Regional Left Ventricular Performance in Infarction and Angina. Clinical Research 22: 153A, 1974.
  • COSBY,R.S., GIDDINGS, J.A., and SEE, J.R.: Coronary Collateral Circulation. Chest 66: 27-31, 1974.
  • GIDDINGS, J.A., COSBY, R.S., and SEE, J.R.: Atrial Contribution to Cardiac Output in Normal Rhythm, Mitral Insufficiency and Mitral Stenosis as Measured by Echcardiography. Clinical Research 22: 304A, 1974.
  • SLAUGHTER, J., SEE, J.R., COSBY, R.S., and GIDDINGS, J.A.: Histopathologic Features of New Versus Old Coronary Collateral Vessels. Clinical Research 22: 304A, 1974.
  • SEE, J.R., COHN, P.F., MARLON, A.M., and COSBY, R.S.: The Effect of Direct Revascularization Surgery on Coronary Collateral Circulation in Man. Clinical Research 22: 686A, 1974.
  • COSBY,R.S., GIDDINGS, J.A., SEE, J.R., MAYO, M., and BOOMERSHINE, P.: The Echocardiogram in Non-Rheumatic Mitral Insufficiency. Chest 66: 642-646, 1974.
  • HOLMAN, B.L., COHN, P.F., SEE, J.R., ROBERTS, B.R., and ADAMS, D.F.: Regional Myocardial Blood Flow after Contrast Hyperemia in Patients with Coronary Artery Disease. Clinical Research 23: 205A, 1975.
  • SEE, J.R., COHN, P.F., HOLMAN, B.L., ROBERTS, B.R., and ADAMS, D.F.: Relationship between Regional Myocardial Blood Flow and Left Ventricular Wall Motion in Coronary Artery Disease. Clinicall Research 23: 207A, 1975.
  • COSBY, R.S., SEE, J.R., GIDDINGS, J.A., TALBOT, J.C., ISHIKAWA, R., BUGGS, H., and MAYO, M.: Left Ventricular Dyskinesia in Infarction and Angina. American Journal of Medicine
    59: 13-20, 1975.
  • COSBY,R.S., GIDDINGS, J.A., and SEE, J.R.: Complications of Coronary Arteriograpphy. American Heart Journal 89 :259, 1975.
  • COSBY,R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Chronic Papillary Muscle Dysfunction: Echocardiographics and Clinical Findings. Western Society for Clinical Research 33: 124A,
    1975.
  • SEE, J.R., MARLON, A.M., FIEKES, H.L., and COSBY, R.S.: Effect of Direct Revascularization Surgery on Coronary Collateral Circulation in Man. American Journal of Cardiology 36: 734-738, 1975.
  • HOLMAN, B.L., COHN, P.F., SEE, J.R., IDIONE, J., and ADAMS, D.F.: Measurement of Myocardial Blood Flow with Xe 133 both at Rest and after Contrast Hyperemia. Journal of Nuclear Medicine 16: 536, 1975.
  • COSBY, R.S., SEE, J.R., GIDDINGS, J.A., and COPELAND, W.J.: Factors Associated with Survival Following Primary Ventricular Fibrillation. Clinical Research 24: 81A, 1976.
  • HOLMAN, B.L., COHN, P.F., ADAMS, D.F., and SEE, J.R., et al.: Regional Myocardial Blood Flow during Hyperemia by Contrast Agents in Patients with Coronary Artery Disease. American Journal of Cardiology 38: 416-421, 1976.
  • SEE, J.R., COHN, P.F., HOLMAN, B.L., et al.: Regional Myocardial Blood Flow in Coronary Artery Disease with and without Ventricular Asynergy. Journal of Nuclear Medicine 16: 567, 1975.
  • COSBY, R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Late Complications of Myocardial Infarction. JAMA 236: 1717-1720, 1976.
  • COHN, P.F., MADDOX, D.E., HOLMAN, B.L., SEE, J.R., et al.: Effect of Sublingual Nitroglycerin on Regional Myocardial Blood Flow in Patients with Coronary Artery Disease. Circulation 11- 174, 1976.
  • MADDOX, D.E., SEE, J.R., HOLMAN, B.L., et al.: Effect of Coronary Collaterals on Regional Myocardial Blood Flow. Circulation 54: 11-231, 1976.
  • SEE, J.R., COHN, P.F., HOLMAN, B.L., et al.: Angiographic Abnormalities Associated with Alterations in Regional Myocardial Blood Flow in Patients with Coronary Artery Disease. British Heart Journal XXXVIII, No. 12: 1278-1285, 1976.
  • COHN, P.F., MADDOX, D.E., HOLMAN, B.L., MARKIS, J.E., ADAMS, D.F., SEE, J.R., et al.: Effect on Sublingually Administered Nitroglycerin on Regional Myocardial Blood Flow in Patients with Coronary Artery Disease. American Journal of Cardiology 39: 672-678, 1977.
  • COSBY, R.S., GIDDINGS, J.A., and SEE, J.R.: Echocardiographic Characteristics of Rheumatic and Non-Rheumatic Mitral Insufficiency. Clinical Research 25: 214A, 1977.
  • COSBY, R.S., SEE, J.R., GIDDINGS, J.A., and MAYO, M.: Echocardiographic Evidence of Papillary Muscle Dysfunction in Coronary Artery Disease. Ultrasound in Medicine 3A: 209-210, 1977.
  • SEE, J.R., HOLMAN, B.L., MADDOX, D.E., ADAMS, D.F., and COHN, P.F.: Markedly Reduced Regional Myocardial Blood Flow as a Predictor of Nonviable Myocardium in Areas of Abnormal Wall Motion. Circulation 56: 111-151, 1977.
  • ROBERTS, B.R., COHN, P.F., HOLMAN, B.L., ADAMS, D.F., and SEE, J.R.: Comparison between Regional Myocardial Blood Flow Measurements and Results of Exercise Tests. Catherization and Cardiovascular Diagnosis 3: 359-366, 1977.
  • SEE, J.R., WHIGHAM, H., COSBY, R.S., PETERSON, R., BRIGGS, H., GARDNER, R., PONTIUS, C.N., and CARLI, T.: Instantaneous Changes in Myocardial Blood Flow and Mean Arterial Pressure during Left Atrial Infusion of Prostaglandin E-1. Clinical Research 26, No. 2, 97A, February 1978.
  • SEE, J.R., COSBY, R.S., GIDDINGS, J.A., and MAYO, M.: Papillary Muscle Dysfunction and Mitral Insufficiency Associated with Myocardial Infarction. Cardiovascular Medicine 3, No. 3: 279-284, March 1978.
  • SEE, J.R., and COSBY, R.S., editors: Myocardial Infarction in the Spectrum of Ischemic Heart Disease. Advances in Cardiology, Vol. 23, S. Karger: Basel, 1978.
  • SEE, J.R., ARGUE, R.L., SILVERIA, R.A., KWON, K., DEMMAN, J.D., KUNELIS, C.T., MATSU NO, M., and COSBY, R.S.: Regional Myocardial Blood Flow in Regions of Prior Infarction Advances in Cardiology, Vol. 23, Karger: Basel, 82-92, 1978.
  • COSBY, R.S., GIDDINGS, J.A., SEE, J.R., and MAYO, M.: Late Complications of Myocardial Infarction. Advances in Cardiology, Vol. 23, Karger: Basel 73-81, 1978.
  • SEE, J.R., COHN, P.F., HOLMAN, B.L., ADAMS, D.F., and MADDOX, D.E.: Significance of Reduced Regional Myocardial Blood Flow in Asynergic Areas Evaluated with Interventional Ventriculography. American Journal of Cardiology, Vol. 43, 179-186, February 1979.
  • SEE, J.R., KWON, K., ARGUE, R.L., JENKINS, D., and MADDOX, D.E.: Radionuclide Evaluation of the Effect on Nitroglycerin on Left Ventricular Performance after Revascularization. Clinical Research, Vol. 28, No, 2, 186A, April 1980.
  • COHN, P.F., MADDOX, D.E., HOLMAN, B.L., and SEE, J.R.: Effect of Coronary Collateral Vessels on Regional Myocardial Blood Flow in Patients with Coronary Artery Disease. American Journal of Cardiology, Vol. 46, 359-364, September 1980.
  • KWON, K. FIRPO, R., SEE, J.R., and JENKINS, D.: Mortality and Morbidity in Myocardial Revascularization: Effect of Additional Surgical Procedures. XI Inter- American Congress of Cardiology, San Juan, Puerto Rico, September 1980.
  • KWON, K. FIRPO, R., GREEN, J., SEE, J.R., and JENKINS, D.: Operative Mortality and Morbidity with Angiographic Comparison between a Control Group and Patients Requiring Repeat Myocardial Revascularization. Clinical Research Vol. 30, No. 2, 199A, 1982.
  • GREEN, J., SEE, J.R., KWON, K.., MIKULESKY, D., GRAINS, P., and HENDERSON, B.: Serial Radionuclide Ventriculographic Studies of Left Ventricular Function and Contractile Reserve Two Years after Revascularization. Clinical Research, April 1983.
  • SEE, J.R., LIEBER, I.H., MATTHEWS, O.H., and SHELL, W.E.: Effect of Intracoronary Prostaglandin E-1 on Myocardial Blood Flow before and after Coronary Angioplasty in Man. Circulation, Vol. 72, Suppl. III, October 1985.
  • SHELL, W.E., KIVOWITZ, C.F., RUBIN, S.B., and SEE, J.R.: Medical Treatment of Silent Myocardial Ischemia with use of Transdermal Nitroglycerin. American Heart Journal, March 1986.
  • SHELL, W.E., SEE, J.R., et al.: Measurement of Myocardial Blood Flow with Non-Radioactive Microspheres. Circulation, Vol. 72, Suppl. II, October 1985.
  • SEE, J.R., SHELL, W.E., MATTHEWS, O., CANIZALES, C., VARGAS, M., GIDDINGS, J.A., and CERRONE, J.: Prostaglandin E-1 Infusion after Angioplasty in Man Inhibits Abrupt Occlusion and
    Early Restenosis. Advances In Prostaglandin, Thromboxane, and Leukotriene Research, Prostaglandins and Related Compounds, Raven Press, Pages 261-271, 1988.
  • SEE, J.R., and SHELL, W.E.: Prostaglandins in Angioplasty. Applied Cardiopulmonary Pathophysiology. 2: 193-198, Kluwer Academic Publishers, Dordrecht, printed in The Netherlands, 1988.
  • SEE, J.R., et al.: In-hospital acute closure after coronary angioplasty: a randomized double-blind study utilizing intravenous prostaglandin E-1 infusion. Prospects and strategies in Cardiovascular Research, symposium held in Maastricht, The Netherlands, 1988.
  • SEE, J.R., SHELL, W.E., MCLAUGHLIN, R.T., Jr.: Detection of Pulmonary Emboli by X-ray Visualization of Biodegradable Microspheres Impregnated with Iodinated Contrast. Circulation, October 1988, Part II, Vol. 78, No. 4.
  • TOBIS, J., OAKES, D., SATO, D., NALCIOGLU, O., JOHNSTON, W.D., MALLERY, J., SEE, J.R., QU, L., REESE, T., PAYNTER, J., MONTELLI, S., and HENRY, W.L.: Minimal Luminal
    Diameter Versus Percent Diameter Narrowing for Assessing Coronary Artery Diseases. Cardiology Board Review, Noninvasive and Invasive Methods of Cardiovascular Diagnosis, Vol.
    6, No. 6, June 1989.
  • SEE, J.R.: Serum Retinal Levels as a Method of Measuring Dietary Fat Absorption. Clinical Research, April 1991.
  • SEE, J.R.: Effect of High Dose Angiotensin – Converting Enzyme Inhibition on Restenosis: Final results of the MARCATOR Study, a multicenter, double-blind, placebo-controlled trial of
    Cilazapril. Faxon, David P., on behalf on the MARCATOR Study Group, Principal Investigator Jackie R. See, M.D., La Mirada, California. Journal of the American College of Cardiology, Vol. 25, No. 2, February 1995: 362-9.
  • SEE, D.M., SEE, J.R., CLARK, T., and TILLES, J.: Successful Immunization of Mice Using Liposomes Containing Inactivated, Prototype Strains of All Six Types of Coxsackie Group B
    Viruses. Vaccine Research, Vol. 6, No. 1, Pages 27-32, 1997.
  • KHEMKA, V., SEE, D.M., SEE, J.R., CHANG, J., CHOU, S., and TILLES, J.G.: The Capacity of a Combined Liposomal Hepatitis B and C Vaccine to Stimulate Humoral and Cellular Responses
    in Mice. Viral Immunology, Vol. 11, No. 2, Pages 73-78, 1998.

PRINCIPAL INVESTIGATOR

  • January 19, 2008, Lancet Journal, Volume 371, Issue 9608, Pages 228-236. Results of a
    non-specific immunomodulation therapy in chronic heart failure (ACCLAIM trial): a
    placebo-controlled randomized trial.
  • April 10, 2006, AstraZeneca LP, Wilmington, DE. A 6-week, open-label, dose-comparison
    study to evaluate the safety and efficacy of rosuvastatin vs atoravastatin, pravastatin and
    simvastatin in subjects with hypercholesterolemia.

HOSPITAL STAFF POSITIONS
Western Medical Center, 1025 S. Anaheim Blvd., Anaheim California 92805
Courtesy Staff, Department of Cardiology 1983 – 2012

RESEARCH PAPERS PRESENTED

  1. April 1972, Inter American Congress of Cardiology, San Francisco, California.
    Thromboembolism Following Coronary Angiography.
  2. February 1972, Regional Meeting, American College of Physicians. Beverly Hills, California.
    Thromboembolism Following Coronary Angioplasty.
  3. January 10, 1975, Eastern Section, American Federation for Clinical Research, Boston,
    Massachusetts. The Effect of Direct Revascularization Surgery on Coronary Collateral
    Circulation in Man.
  4. March 1975, University of California, Irvine, College of Medicine and Pasadena
    Cardiovascular Research Foundation, Newport Beach, California. Pathophysiology of
    Coronary Heart Disease.
  5. June 18, 1975, Annual Meeting, New England Society of Nuclear Medicine, Philadelphia,
    Pennsylvania. Regional Myocardial Blood Flow (RMBF) in Coronary Artery Disease (CAD)
    with and without Ventricular Asynergy.
  6. October 24, 1975, University of California Fall Meeting, Lake Arrowhead, California. The
    Effect of Direct Revascularization Surgery on the Collateral Circulation in Man.
  7. November 17, 1975, American Heart Association Meeting, Anaheim, California.
    Angiographic Abnormalities Associated with Alteration in Regional Myocardial Blood Flow in
    Coronary Artery Disease.
  8. April 2, 1976, Foundation for Cardiovascular Research and the Hospital of the Good
    Samaritan, Palm Springs, California. Postextrasystolic Potentiation: Interrelation between
    Cycle Length and Ventricular Contractility.
  9. March 15, 1977, Foundation for Cardiovascular Research and the Hospital of the Good
    Samaritan, Palm Springs, California. Regional Myocardial Blood Flow in the Regions of Prior
    Myocardial Infarction before and after Revascularization.
  10. November 28, 1977, American Heart Association 50th Scientific Session, Miami Beach,
    Florida. Markedly Reduced Regional Myocardial Blood Flow as a Predictor of Non-Viable
    Myocardium in Areas of Abnormal Wall Motion.
  11. May 1, 1978, American Federation for Clinical Research National Meeting, San Francisco,
    California. Instantaneous Changes in Myocardial Blood Flow, Cardiac Output, and Mean
    Arterial Pressure During Left Atrial Infusion of Prostaglandin E-1.
  12. September 10, 1980, XI Inter American Congress of Cardiology, San Juan, Puerto Rico.
    Radionuclide Evaluation of Nitroglycerin Induced Regional Contractile Reserve before and
    after Revascularization.
  13. April 2, 1982, Cardiovacular Update, Sponsored by the American Heart Association, Kern
    County Chapter and Foundation for Applied Research and Technology. Rio Bravo Ranch,
    Bakersfield, California. Nuclear Cardiology: Value in Determining Operative Candidates and
    Postoperative Results.
  14. November 13, 1985, American Heart Association’s 58th Annual Scientific Sessions,
    Washington, D.C. Effect of Intracoronary PGE-1 on Myocardial Blood Flow pre- and post-
    Coronary Angioplasty in Man.
  15. June 4, 1986, 6th International Conference on Prostaglandins and Related Compounds,
    Florence, Italy. Prostaglandin E-1 Infusion after Angioplasty in Man Inhibits Abrupt Occlusion
    in Early Restenosis.
  16. November 20, 1987, Applied Physiology in Cardio-Respiratory Emergencies, Erasmus
    University Rotterdam, Netherlands. Prostaglandins in Angioplasty.
  17. November 16, 1988, American Heart Association’s 61st Annual Scientific Sessions,
    Washington, D.C. Detection of Pulmonary Emboli by X-ray Visualization of Biodegradable
    Microspheres Impregnated with Iodinated Contrast.
  18. October 2 – 5, 1988, Prospects and Strategies in Cardiovascular Research, Maastricht, The
    Netherlands. Prostaglandins in Angioplasty.
  19. June 27 – July 1, 1993, 3rd International Conference on Preventive Cardiology, Oslo, Norway,
    Beta-sitosterol Pectin Complex Inhibits Dietary Cholesterol Uptake (co-author).
  20. April 1997, American College of Urology Annual Symposium, New Orleans, Louisiana.
    Lyophilized Liposomal PGE-1 Usage in Erectile Dysfunction (co-author).
  21. October 2 – 4, 1997, XI International Symposium on Atherosclerosis, Abbaye De Royaumont,
    France, Reduction of LDL-c Using a Beta-sitosterol Pectin Complex (co-author).
  22. October 1998, Symposium on Sexual Dysfunction, Boston, Massachusetts. MRI Flow
    Studies of Female Pelvic Blood Flow in Rabbits in the Presence of PGE-1 Topical Lotion (coauthor).

INVITED LECTURES GIVEN

  1. August 15, 1983, “Percutaneous Transluminal Coronary Angioplasty,” Associated Alumni,
    UCI-CCM Scientific Sessions, Waialae, Maui.
  2. October 26, 1983, “Percutaneous Transluminal Angioplasty Procedure,” La Habra
    Community Hospital, Medical and Nursing Staff.
  3. February 15, 1984, “Stress as a Cause of Cardiovascular Disease: Is it Anyone’s Fault?”
    Association of Southern California Defense Council, Annual Winter Seminar at Banff Springs
    Hotel, Alberta, Canada.
  4. April 26, 1985, “Percutaneous Transluminal Coronary Angioplasty,” Guest Faculty, Western
    Medical Center, Anaheim, California.
  5. February 2, 1985, “Health Care Legislation: It’s Impact on the Profession,” 8th Annual
    Association of Southern California Defense Council Seminar, Steamboat Springs, Colorado.
  6. November 10 – 14, 1985, “Effect of Intracoronary PGE-1 on Myocardial Blood Flow pre- and post-Angioplasty in Man,” American Heart Association 58th Scientific Session, Washington, D.C.
  7. December 16, 1986, “Overview of Silent Ischemia,” Baylor College of Medicine, Texas Medical Center, Houston, Texas.
  8. March 4, 1986, 9th Annual Association of Southern California Defense Council Snow
    Seminar, Teton Village, Jackson Hole, Wyoming. “Health Care Plans, Cost Cutting vs.
    Quality of Care, Role of Malpractice Litigation.”
  9. March 14, 1986, Cardiovascular Seminar at Long Beach Memorial Hospital A.A.C.N. of the
    Greater Long Beach/Orange County Chapter. “Prostaglandin PGE-1.”
  10. June 9, 1986, Loma Linda University Medical Center, School of Medicine, Medical Grand
    Rounds, “Prostaglandins in Coronary Angioplasty.”
  11. June 4, 1986, “PGE-1 and Restenosis,” 6th Annual International Conference on
    Prostaglandins, Florence, Italy.
  12. July 8, 1986, “Complications of Acute Myocardial Infarction,” UCI-CCM Annual Conference,
    Maui, Hawaii.
  13. July 1984, “Angioplasty in Acute Myocardial Infarction,” Associated Alumni, UCI-CCM
    Scientific Session, Mauna Lani, Hawaii.
  14. May 15, 1986, “Angioplasty in Man,” Biology of Heart Disease Seminar, University of
    California, Irvine, California.
  15. January 28, 1986, “Prostaglandin Therapy in the PTCA Patient,” Western Medical Center,
    Anaheim, California, Education Program of RN’s and LVN’s.
  16. September 18, 1986, “Prostaglandin E-1 Infusion after Angioplasty in Man Inhibits Abrupt
    Occlusion and Early Restenosis,” Harvard Medical School, Brockton/West Roxbury, Veterans
    Administration Medical Center, Boston, Massachusetts.
  17. October 25, 1986, “Prostaglandin: Effects on Early and Late Restenosis,” Update 1986
    PTCA and Acute Myocardial Infarction, presented by Advanced Cardiovascular Systems,
    Inc., The Upjohn Company, La Jolla, California.
  18. November 15, 1986, “Thrombolysin,” Associated Alumni University of California, Irvine,
    Scientific Sessions, Palm Desert, California.
  19. October 6, 1986, “Current Trends in Angioplasty,” Continuing Medical Education, Western
    Medical Center, Anaheim, California.
  20. February 19, 1987, “The Use of Prostaglandins in PTCA,” Leeds, United Kingdom.
  21. February 20, 1987, “Pharmacological Control of Restenosis Following PTCA,” St. Thomas
    Hospital (The Rayne Instititute), London, United Kingdom.
  22. February 24, 1987, “The Use of PGE-1 in Coronary Angioplasty,” Belgium Group for
    International Cardiology, Brussels, Belgium.
  23. Fenruary 26, 1987, “The Use of Prostaglandins in PTCA,” Oporto, Portugal.
  24. March 11, 1987, “New Developments in Medicine and the Law,” the 32nd Annual Association
    of Southern California Defense Council, Snow Seminar, Snowmass, Colorado.
  25. July 7 – 10, 1987, “Complications of Acute Myocardial Infarction,” Continuing Medical
    Education, Associated Alumni UCI-CCM, Maui, Hawaii.
  26. April 2 – 3, 1987, “Prostaglandins Therapy,” Frontiers in Cardiology for the Primary Care
    Physician 4th Annual Seminar, Baptist Memorial Hospital, The University of Tennessee,
    Memphis, Tennessee.
  27. May 26, 1987, “Percutaneous Transluminal Coronary Angioplasty: the Effects of
    Prostaglandins as Therapeutics,” Society of Critical Care Medicine, Anaheim, California.
  28. July 29, 1987, “Recent Advances in Cardiology,” Associated Alumni UCI-CCM, Continuing
    Medical Education, Lake Tahoe, Nevada.
  29. September 16, 1987, “PTCA and Restenosis,” Medical Subspecialty Lectures University of
    California, Irvine.
  30. November 20, 1987, “Prostaglandins in Angioplasty,” Applied Physiology in Cardio-
    Respiratory Emergencies, Erasmus Universiteit, Rotterdam, Netherlands.
  31. November 23, 1987, “Prostaglandins,” Cardiovascular Nursing Symposium 1988 American
    Heart Association, Orange County Chapter, Irvine, California.
  32. February 26, 1988, “Prostaglandins,” Cardiovascular Nursing Symposium 1988 American
    Heart Association, Orange County Chapter, Irvine, California.
  33. April 15, 1988, “Percutaneous Transluminal Coronary Angioplasty,” University of California,
    Irvine Medical Center, Department of Medicine, Cardiology Division, Cardiology Research
    Conference, Orange, California.
  34. May 3, 1988, “Complex Coronary Angioplasty,” Continuing Medical Education Program,
    Medical Center of La Mirada, Gateway Plaza Holiday Inn, La Mirada, California.
  35. June 6, 1988, “PGE-1 in Angioplasty,” University of Graz, Vienna, Austria.
  36. June 7, 1988, “PGE-1 in Angioplasty,” University Clinic, Innsbruck, Austria.
  37. July 19, 1988, “Thrombolytic Therapy for Acute M.I.,” Family Health Plan Hospital, Fountain
    Valley, California.
  38. October 3, 1988, “Prostaglandins in Angioplasty,” International Congress, “Prospects and
    Strategies in Cardiovascular Research,” Maastricht, Netherlands.
  39. October 7, 1988, “Prostaglandins in Angioplasty,” Upjohn International Visiting Professor
    Program, Belgium.
  40. October 9, 1988, “Prostaglandins in Angioplasty,” Upjohn International Visiting Professor
    Program, Belgium.
  41. October 22, 1988, “Prostaglandins in Angioplasty,” Regional Symposium, Palm Desert,
    California.
  42. November 5, 1988, “Comparison of Multi-vessel Angioplasty with CABG,” 14th Annual
    Primary Care Seminar, Nu-Med Hospitals, Monterey, California.
  43. February 16, 1989, “Sorting Out the Significance of Prostaglandins in Cardiology,” the
    Scripps Memorial Hospital Cardiovascular Institute and the Scripps Memorial Hospital’s
    Foundation, La Jolla, California.
  44. March 4 – 11, 1989, “New Developments in Medicine and the Law,” 12th Annual Southern
    California ASCDC Snow Seminar, Breckenridge, Colorado.
  45. May 9, 1989, Medical Center of La Mirada Celebration of National Hospital Week,
    “Wellspring,” a Chamber Mixer, Southern California Heart Institute “Future Plans of SCHI,” La Mirada, California.
  46. August 11, 1989, “Clinical Use of Prostaglandins,” Associated Alumni UCI-CCM Annual
    Scientific Sessions, Lake Tahoe, Nevada.
  47. August 25, 1989, “Recent Advances in Cardiology,” Southern California Heart Institute,
    Dedication of Interventional Cardiology Laboratory in the Name of Richard S. Cosby, M.D.
  48. February 28, 1990, “Patients and Health Insurance,” 13th Annual Southern California ASCDC
    Snow Seminar, Whistler, British Columbia, Canada.
  49. August 7, 1990, “Cholesterol and Myths Versus Facts in Coronary Disease,” Associated
    Alumni UCI-CCM Annual Scientific Session, Lake Tahoe, Nevada.
  50. October 13 – 14, 1993, “Methods to Stabilize Liposomal Preparations,” Monnheim, Germany.

US and International Patents issued, listing available upon request, 1983 – Present

US and International Patents applied-for and continuations-in-part available upon request, 1983 – Present

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